A 438079 from UNITED STATES BIOLOGICAL

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Product NameA 438079
DescriptionPurity ~99% (HPLC). A potent, competitive, and selective antagonist of P2X7 purinergic receptor (pIC50 = 6.5nM and 6.9nM for rat and human P2X7 receptor, respectively). Shown to reduce ATP-induced reactive oxygen species formation in MEL cells by about 87% (~10uM) and blocks BzATP-stimulated changes in intracellular calcium concentrations (IC50 = 100 and 300nM at rat and human P2X7 receptors, respectively. Solubility (100mM): DMSO Carbon Content: 44-56% Hydrogen Content: 2.30-3.70% Nitrogen Content: 19-21% Water by CHN (mol): ≤1mol Primary Target: P2X7
Size10mg
Concentrationn/a
Applicationsn/a
Other Names3-((5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methyl)pyridine Hydrochloride; P2X7 Purinergic Receptor Antagonist; A 438079; A438079; A-438079
Gene, Accession, CAS #n/a
Catalog #217134
Priceplease inquire
Order / More InfoA 438079 from UNITED STATES BIOLOGICAL
Product Specific Referencesn/a
UNITED STATES BIOLOGICAL
UNITED STATES BIOLOGICAL
UNITED STATES BIOLOGICAL
4 Technology Way
Salem MA 01970
P: 781-639-5092
P: 800-520-3011
F: 978-594-8052

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