(S)-BAY-598 |
A selective inhibitor of SMYD2 with IC50 values of 27 nM and in vitro and… |
5 mg |
18238-5 |
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(S)-BAY-598 |
A selective inhibitor of SMYD2 with IC50 values of 27 nM and in vitro and… |
500 µg |
18238-500 |
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SB-772077B (hydrochloride) |
A ROCK inhibitor (IC50s = 5.6 and 6 nM for ROCK1 and ROCK2, respectively);… |
1 mg |
30975-1 |
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SB-772077B (hydrochloride) |
A ROCK inhibitor (IC50s = 5.6 and 6 nM for ROCK1 and ROCK2, respectively);… |
5 mg |
30975-5 |
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SBC-110736 |
A PCSK9 inhibitor; increases LDLR levels in HepG2 cells expressing PCSK9 a… |
1 mg |
23103-1 |
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SBC-110736 |
A PCSK9 inhibitor; increases LDLR levels in HepG2 cells expressing PCSK9 a… |
10 mg |
23103-10 |
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SBC-110736 |
A PCSK9 inhibitor; increases LDLR levels in HepG2 cells expressing PCSK9 a… |
25 mg |
23103-25 |
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SBC-110736 |
A PCSK9 inhibitor; increases LDLR levels in HepG2 cells expressing PCSK9 a… |
5 mg |
23103-5 |
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SBC-115076 |
A modulator of PCSK9 action that blocks LDLR degradation, increasing the u… |
1 mg |
19134-1 |
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SBC-115076 |
A modulator of PCSK9 action that blocks LDLR degradation, increasing the u… |
10 mg |
19134-10 |
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SBC-115076 |
A modulator of PCSK9 action that blocks LDLR degradation, increasing the u… |
25 mg |
19134-25 |
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SBC-115076 |
A modulator of PCSK9 action that blocks LDLR degradation, increasing the u… |
5 mg |
19134-5 |
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SB-3CT |
A selective, mechanism-based inhibitor of MMP-2 and MMP-9 (Kis = 28 and 40… |
1 mg |
16337-1 |
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SB-3CT |
A selective, mechanism-based inhibitor of MMP-2 and MMP-9 (Kis = 28 and 40… |
5 mg |
16337-5 |
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SB-3CT |
A selective, mechanism-based inhibitor of MMP-2 and MMP-9 (Kis = 28 and 40… |
500 µg |
16337-500 |
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SBE 13 (hydrochloride) |
A potent inhibitor of Plk1(IC50 = 0.2 nM) that targets the inactive confor… |
10 mg |
21241-10 |
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SBE 13 (hydrochloride) |
A potent inhibitor of Plk1(IC50 = 0.2 nM) that targets the inactive confor… |
25 mg |
21241-25 |
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SBE 13 (hydrochloride) |
A potent inhibitor of Plk1(IC50 = 0.2 nM) that targets the inactive confor… |
5 mg |
21241-5 |
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SBE 13 (hydrochloride) |
A potent inhibitor of Plk1(IC50 = 0.2 nM) that targets the inactive confor… |
50 mg |
21241-50 |
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SBFI AM |
A membrane-permeant, fluorescent Na+ indicator dye; increasing concentrati… |
1 mg |
18764-1 |
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SB-431542 (hydrate) |
A potent and selective inhibitor of the TGF-β1 receptor ALK5 (IC50 =… |
1 mg |
13031-1 |
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SB-431542 (hydrate) |
A potent and selective inhibitor of the TGF-β1 receptor ALK5 (IC50 =… |
10 mg |
13031-10 |
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SB-431542 (hydrate) |
A potent and selective inhibitor of the TGF-β1 receptor ALK5 (IC50 =… |
25 mg |
13031-25 |
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SB-431542 (hydrate) |
A potent and selective inhibitor of the TGF-β1 receptor ALK5 (IC50 =… |
5 mg |
13031-5 |
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SB 202190 (hydrochloride) |
A potent, selective, and cell-permeable inhibitor of p38 MAP kinases; inhi… |
1 mg |
21201-1 |
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SB 202190 (hydrochloride) |
A potent, selective, and cell-permeable inhibitor of p38 MAP kinases; inhi… |
10 mg |
21201-10 |
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SB 202190 (hydrochloride) |
A potent, selective, and cell-permeable inhibitor of p38 MAP kinases; inhi… |
25 mg |
21201-25 |
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SB 202190 (hydrochloride) |
A potent, selective, and cell-permeable inhibitor of p38 MAP kinases; inhi… |
5 mg |
21201-5 |
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SB 203580 (hydrochloride) |
A formulation with greater solubility in organic solvents than standard SB… |
10 mg |
13344-10 |
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SB 203580 (hydrochloride) |
A formulation with greater solubility in organic solvents than standard SB… |
25 mg |
13344-25 |
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SB 203580 (hydrochloride) |
A formulation with greater solubility in organic solvents than standard SB… |
5 mg |
13344-5 |
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SB 203580 (hydrochloride) |
A formulation with greater solubility in organic solvents than standard SB… |
50 mg |
13344-50 |
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SB-200646 (hydrochloride) |
A dual antagonist of 5-HT2C (Ki = 125 nM in isolated rat cortex) and 5-HT2… |
1 mg |
30973-1 |
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SB-200646 (hydrochloride) |
A dual antagonist of 5-HT2C (Ki = 125 nM in isolated rat cortex) and 5-HT2… |
10 mg |
30973-10 |
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SB-200646 (hydrochloride) |
A dual antagonist of 5-HT2C (Ki = 125 nM in isolated rat cortex) and 5-HT2… |
5 mg |
30973-5 |
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SB-206553 (hydrochloride) |
A 5-HT2C (Ki = 12.6 nM) and 5-HT2B receptor antagonist; selective for 5-HT… |
10 mg |
34263-10 |
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SB-206553 (hydrochloride) |
A 5-HT2C (Ki = 12.6 nM) and 5-HT2B receptor antagonist; selective for 5-HT… |
25 mg |
34263-25 |
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SB-206553 (hydrochloride) |
A 5-HT2C (Ki = 12.6 nM) and 5-HT2B receptor antagonist; selective for 5-HT… |
5 mg |
34263-5 |
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SB-206553 (hydrochloride) |
A 5-HT2C (Ki = 12.6 nM) and 5-HT2B receptor antagonist; selective for 5-HT… |
50 mg |
34263-50 |
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SB-216641 (hydrochloride) |
A 5-HT1B receptor antagonist; binds to 5-HT1B receptors (Ki = 1 nM); selec… |
1 mg |
32837-1 |
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SB-216641 (hydrochloride) |
A 5-HT1B receptor antagonist; binds to 5-HT1B receptors (Ki = 1 nM); selec… |
10 mg |
32837-10 |
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SB-216641 (hydrochloride) |
A 5-HT1B receptor antagonist; binds to 5-HT1B receptors (Ki = 1 nM); selec… |
5 mg |
32837-5 |
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SB-224289 (hydrochloride) |
A potent 5-HT1B inverse agonist (pKi = 8.16) that displays >75-fold select… |
10 mg |
17036-10 |
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SB-224289 (hydrochloride) |
A potent 5-HT1B inverse agonist (pKi = 8.16) that displays >75-fold select… |
25 mg |
17036-25 |
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SB-224289 (hydrochloride) |
A potent 5-HT1B inverse agonist (pKi = 8.16) that displays >75-fold select… |
5 mg |
17036-5 |
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SB-224289 (hydrochloride) |
A potent 5-HT1B inverse agonist (pKi = 8.16) that displays >75-fold select… |
50 mg |
17036-50 |
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SB-242084 (hydrochloride) |
An antagonist of the 5-HT2C receptor (pKi = 9.0), with at least 100-fold m… |
1 mg |
10096-1 |
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SB-242084 (hydrochloride) |
An antagonist of the 5-HT2C receptor (pKi = 9.0), with at least 100-fold m… |
10 mg |
10096-10 |
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SB-242084 (hydrochloride) |
An antagonist of the 5-HT2C receptor (pKi = 9.0), with at least 100-fold m… |
5 mg |
10096-5 |
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SB-243213 (hydrochloride) |
A 5-HT2C receptor inverse agonist; selective for 5-HT2C over the 5-HT2A an… |
1 mg |
36217-1 |
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SB-243213 (hydrochloride) |
A 5-HT2C receptor inverse agonist; selective for 5-HT2C over the 5-HT2A an… |
5 mg |
36217-5 |
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SB-258585 (hydrochloride) |
A potent, selective antagonist of the serotonin 5-HT6 receptor (pKi = 8.53… |
1 mg |
17416-1 |
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SB-258585 (hydrochloride) |
A potent, selective antagonist of the serotonin 5-HT6 receptor (pKi = 8.53… |
10 mg |
17416-10 |
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SB-258585 (hydrochloride) |
A potent, selective antagonist of the serotonin 5-HT6 receptor (pKi = 8.53… |
5 mg |
17416-5 |
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SB-258585 (hydrochloride) |
A potent, selective antagonist of the serotonin 5-HT6 receptor (pKi = 8.53… |
50 mg |
17416-50 |
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SB-269970 (hydrochloride) |
A potent 5-HT7A antagonist (pKi = 8.9) that demonstrates >50-fold binding… |
10 mg |
17081-10 |
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SB-269970 (hydrochloride) |
A potent 5-HT7A antagonist (pKi = 8.9) that demonstrates >50-fold binding… |
25 mg |
17081-25 |
More Info
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SB-269970 (hydrochloride) |
A potent 5-HT7A antagonist (pKi = 8.9) that demonstrates >50-fold binding… |
5 mg |
17081-5 |
More Info
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SB-269970 (hydrochloride) |
A potent 5-HT7A antagonist (pKi = 8.9) that demonstrates >50-fold binding… |
50 mg |
17081-50 |
More Info
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SB-271046 (hydrochloride) |
A selective, orally-available antagonist of the 5-HT6 receptor (pKi = 9.02… |
10 mg |
18513-10 |
More Info
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SB-271046 (hydrochloride) |
A selective, orally-available antagonist of the 5-HT6 receptor (pKi = 9.02… |
25 mg |
18513-25 |
More Info
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SB-271046 (hydrochloride) |
A selective, orally-available antagonist of the 5-HT6 receptor (pKi = 9.02… |
5 mg |
18513-5 |
More Info
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SB-271046 (hydrochloride) |
A selective, orally-available antagonist of the 5-HT6 receptor (pKi = 9.02… |
50 mg |
18513-50 |
More Info
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SB-399885 (hydrochloride) |
A 5-HT6 receptor antagonist (Ki = 0.72 nM); >200-fold selective for 5-HT6… |
10 mg |
32817-10 |
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SB-399885 (hydrochloride) |
A 5-HT6 receptor antagonist (Ki = 0.72 nM); >200-fold selective for 5-HT6… |
25 mg |
32817-25 |
More Info
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SB-399885 (hydrochloride) |
A 5-HT6 receptor antagonist (Ki = 0.72 nM); >200-fold selective for 5-HT6… |
5 mg |
32817-5 |
More Info
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SB-399885 (hydrochloride) |
A 5-HT6 receptor antagonist (Ki = 0.72 nM); >200-fold selective for 5-HT6… |
50 mg |
32817-50 |
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SB-743921 (hydrochloride) |
An Eg5 inhibitor (Ki = 0.5 nM for microtubule-stimulated ATPase activity);… |
1 mg |
18384-1 |
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SB-743921 (hydrochloride) |
An Eg5 inhibitor (Ki = 0.5 nM for microtubule-stimulated ATPase activity);… |
10 mg |
18384-10 |
More Info
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SB-743921 (hydrochloride) |
An Eg5 inhibitor (Ki = 0.5 nM for microtubule-stimulated ATPase activity);… |
5 mg |
18384-5 |
More Info
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SB-743921 (hydrochloride) |
An Eg5 inhibitor (Ki = 0.5 nM for microtubule-stimulated ATPase activity);… |
50 mg |
18384-50 |
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SBI-0206965 |
An inhibitor of ULK1 (IC50 = 108 nM) that is less effective against ULK2 (… |
10 mg |
18477-10 |
More Info
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SBI-0206965 |
An inhibitor of ULK1 (IC50 = 108 nM) that is less effective against ULK2 (… |
100 mg |
18477-100 |
More Info
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SBI-0206965 |
An inhibitor of ULK1 (IC50 = 108 nM) that is less effective against ULK2 (… |
25 mg |
18477-25 |
More Info
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SBI-0206965 |
An inhibitor of ULK1 (IC50 = 108 nM) that is less effective against ULK2 (… |
5 mg |
18477-5 |
More Info
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