Myeloid/lymphoid Or Mixed-Lineage Leukemia Protein 3 (MLL3) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia Protein 3 (MLL3) antibody, protein, ELISA kits.
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| Antigenic Specificity | Myeloid/lymphoid Or Mixed-Lineage Leukemia Protein 3 (MLL3) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 25 µl, 100 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL family, including MLL3. The MLL SET domain is a histone H3 Lys4 (K4) specific methyltransferase whose activity is stimulated with acetylated H3 peptides. MLL3 maps to 7q36, a chromosome region frequently deleted in myeloid leukaemia. The deduced MLL3 4911-amino acid protein is more closely related to MLL2 than to MLL1 or MLL4. MLL3 has 6 plant homeodomain (PHD) fingers preceded by a cys-rich ZNF1 domain in its N terminus; a high mobility group (HMG) box, an ATPase alpha-beta signature, and a leucine zipper motif in its central region; and 2 C-terminal FY (phe-tyr) motifs and the SET domain preceded by a ZNF2 domain in its C terminus. The predicted protein also contains several putative nuclear localization motifs. Isoform II lacks ZNF1 and the PHD. |
| Immunogen | This MLL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4345-4374 amino acids from the C-terminal region of human MLL3. |
| Other Names | MLL3, HALR, KIAA1506, KMT2C, Histone-lysine N-methyltransferase MLL3, Homologous to ALR protein, Lysine N-methyltransferase 2C, Myeloid/lymphoid or mixed-lineage leukemia protein 3, MLL3, MLL3, MLL3 , MLL3 , HALR, HALR, HALR , HALR , KIAA1506, KIAA1506, KIAA1506 , KIAA1506 , KMT2C, KMT2C, KMT2C , KMT2C , Histone-lysine N-methyltransferase MLL3, Histone-lysine N-methyltransferase MLL3, Histone-lysine N-methyltransferase MLL3 , Histone-lysine N-methyltransferase MLL3 , Homologous to ALR protein, Homologous to ALR protein, Homologous to ALR protein , Homologous to ALR protein , Lysine N-methyltransferase 2C, Lysine N-methyltransferase 2C, Lysine N-methyltransferase 2C , Lysine N-methyltransferase 2C , Myeloid/lymphoid or mixed-lineage leukemia protein 3, Myeloid/lymphoid or mixed-lineage leukemia protein 3, Myeloid/lymphoid or mixed-lineage leukemia protein 3 , Myeloid/lymphoid or mixed-lineage leukemia protein 3 |
| Gene, Accession # | Gene ID: 58508, NCBI: NP_733751.2, UniProt: Q8NEZ4 |
| Catalog # | abx032715 |
| Price | please inquire |
| Order / More Info | Myeloid/lymphoid Or Mixed-Lineage Leukemia Protein 3 (MLL3) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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