Mitogen-Activated Protein Kinase Kinase Kinase 7-Interacting Protein 3 (MAP3K7IP3) Antibody from ABBEXA LTD

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Antigenic SpecificityMitogen-Activated Protein Kinase Kinase Kinase 7-Interacting Protein 3 (MAP3K7IP3)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionThe product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
ImmunogenKLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MAP3K7IP3.
Other NamesMAP3K7IP3, TAB3, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, NF-kappa-B-activating protein 1, TAK1-binding protein 3, TGF-beta-activated kinase 1-binding protein 3, MAP3K7IP3, MAP3K7IP3, MAP3K7IP3 , MAP3K7IP3 , TAB3, TAB3, TAB3 , TAB3 , TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 , TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 , Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 , Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 , NF-kappa-B-activating protein 1, NF-kappa-B-activating protein 1, NF-kappa-B-activating protein 1 , NF-kappa-B-activating protein 1 , TAK1-binding p
Gene, Accession #TAB3, UniProt: Q8N5C8
Catalog #abx029258
Priceplease inquire
Order / More InfoMitogen-Activated Protein Kinase Kinase Kinase 7-Interacting Protein 3 (MAP3K7IP3) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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