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Antigenic Specificity | Mitogen-Activated Protein Kinase Kinase Kinase 7-Interacting Protein 3 (MAP3K7IP3) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. |
Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MAP3K7IP3. |
Other Names | MAP3K7IP3, TAB3, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, NF-kappa-B-activating protein 1, TAK1-binding protein 3, TGF-beta-activated kinase 1-binding protein 3, MAP3K7IP3, MAP3K7IP3, MAP3K7IP3 , MAP3K7IP3 , TAB3, TAB3, TAB3 , TAB3 , TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 , TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 , Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 , Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 , NF-kappa-B-activating protein 1, NF-kappa-B-activating protein 1, NF-kappa-B-activating protein 1 , NF-kappa-B-activating protein 1 , TAK1-binding p |
Gene, Accession # | TAB3, UniProt: Q8N5C8 |
Catalog # | abx029258 |
Price | please inquire |
Order / More Info | Mitogen-Activated Protein Kinase Kinase Kinase 7-Interacting Protein 3 (MAP3K7IP3) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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