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Antigenic Specificity | BAX (BH3 Domain Specific) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bax belongs to the BCL2 protein family. BCL2 family members form hetero or homodimers and act as anti or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bax forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of the Bax gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. |
Immunogen | KLH-conjugated synthetic peptide between 41-76 amino acids from human Bax. |
Other Names | BAX, BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4, BAX, BAX , BAX , BAX, BCL2L4, BCL2L4 , BCL2L4 , BCL2L4, Apoptosis regulator BAX, Apoptosis regulator BAX , Apoptosis regulator BAX , Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl-2-like protein 4 , Bcl-2-like protein 4 , Bcl-2-like protein 4 |
Gene, Accession # | NCBI: NP_004315.1, NP_620116.1, NP_620118.1, NP_620119.2, UniProt: Q07812 |
Catalog # | abx025083 |
Price | please inquire |
Order / More Info | BAX (BH3 Domain Specific) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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