Profilin-1 (PFN1) Antibody from ABBEXA LTD

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Antigenic SpecificityProfilin-1 (PFN1)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat, monkey
Isotypen/a
Formataffinity purified
Size20 µl, 50 µl, 100 µl, 200 µl
Concentration> 0.5 mg/ml
ApplicationsWB
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DescriptionPFN1 antibody is a Rabbit polyclonal antibody against PFN1. The dynamic polymerization and depolymerization of actin filaments, a process governed by external and internal signaling events, is vital for cell motility (immune cell function, migration, invasion, metastasis, angiogenesis), cell division and adhesion. Among the many regulators of actin dynamics are profilins. Profilins are conserved actin binding proteins that affect the rate of actin polymerization by binding actin monomers and promoting the exchange of ADP for ATP (reviewed in 1). Profilins bind to proteins involved in the regulation of actin dynamics including palladin (2), dynamin-1 (3), VASP (4) and N-WASP (5). In mice, knockout of the ubiquitously expressed profilin-1 indicates that the protein is essential for embryonic development (6). Profilin-2 is primarily expressed in brain and functions in the regulation of neurite outgrowth (7), membrane trafficking and endocytosis (3). The recently cloned profilin-3 is expressed in kidney and testes (8).
ImmunogenRecombinant protein of human PFN1.
Other NamesALS18, PFN1, Epididymis tissue protein Li 184a, Profilin I, ALS18, ALS18, ALS18 , ALS18 , PFN1, PFN1, PFN1 , PFN1 , Epididymis tissue protein Li 184a, Epididymis tissue protein Li 184a, Epididymis tissue protein Li 184a , Epididymis tissue protein Li 184a , Profilin I, Profilin I, Profilin I , Profilin I
Gene, Accession #PFN1, Gene ID: 5216, UniProt: P07737
Catalog #abx001078
Priceplease inquire
Order / More InfoProfilin-1 (PFN1) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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