SARS virus Sm Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-SARS virus Sm antibody, protein, ELISA kits.
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| Antigenic Specificity | SARS virus Sm |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | An outbreak of atypical pneumonia, referred to as severe acute respiratory syndrome (SARS) and first identified in Guangdong Province, China, has spread to several countries. The severity of this disease is such that the mortality rate appears to be ~3 to 6%. A number of laboratories worldwidehave undertaken the identification of the causative agent. The National Microbiology Laboratory in Canada obtained the Tor2 isolate from a patient in Toronto, and succeeded in growing a coronavirus-like agent in African Green Monkey Kidney (Vero E6) cells. This coronavirus has been named publicly by the World Health Organization and member laboratories as ?SARS virus? The SARS membrane proteins, including the major proteins S (Spike) and M (Membrane), are inserted into the endoplasmic reticulum Golgi intermediate compartment (ERGIC) while full length replicated RNA (+ strands) assemble with the N (nucleocapsid) protein. The virus then migrates through the Golgi complex and eventually exits the cell, likely by exocytosis. The site of viral attachment to the host cell resides within the S protein. Oligomeric spike (S) glycoproteins extend from SARS membranes. These integral membrane proteins assemble within the endoplasmic reticulum of infected cells and are subsequently endoproteolyzed in the Golgi, generating noncovalently associated S1 and S2 fragments. Once on the surface of infected cells and virions, peripheral S1 fragments bind carcinoembryonic antigen-related cell adhesion molecule (CEACAM) receptors, and this triggers membrane fusion reactions mediated by integral membrane S2 fragments. |
| Immunogen | KLH-conjugated synthetic peptide between 532-562 amino acids from the middle of SARS CoV Spike protein. |
| Other Names | S, Spike glycoprotein, E2, Peplomer protein, Spike protein S1, Spike protein S2, S, S, S , S , Spike glycoprotein, Spike glycoprotein, Spike glycoprotein , Spike glycoprotein , E2, E2, E2 , E2 , Peplomer protein, Peplomer protein, Peplomer protein , Peplomer protein , Spike protein S1, Spike protein S1, Spike protein S1 , Spike protein S1 , Spike protein S2, Spike protein S2, Spike protein S2 , Spike protein S2 |
| Gene, Accession # | UniProt: P59594 |
| Catalog # | abx032684 |
| Price | please inquire |
| Order / More Info | SARS virus Sm Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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