PR/SET Domain-Containing Protein 07 (SET07) Antibody from ABBEXA LTD

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Antigenic SpecificityPR/SET Domain-Containing Protein 07 (SET07)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein G purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionSET07 is a histone methyltransferase that methylates Lys-20 of histone H4. H4 Lys-20 methylation represents a specific tag for epigenetic transcriptional repression. The nuclear SET07 protein, which associates with silent chromatin on euchromatic arms but shows no association with constitutive heterochromatin, prefers nucleosomes as substrate compared to free histones. It appears that SET07 may play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail. Although the SET domain contains the active site of enzymatic activity, both sequences upstream and downstream of the SET domain are required for methyltransferase activity.
ImmunogenKLH-conjugated synthetic peptide between 362-393 amino acids from the C-terminal region of human SET07.
Other NamesSETD8, KMT5A, PRSET7, SET07, SET8, N-lysine methyltransferase SETD8, H4-K20-HMTase SETD8, Histone-lysine N-methyltransferase SETD8, Lysine N-methyltransferase 5A, PR/SET domain-containing protein 07, SET domain-containing protein 8, SETD8, SETD8, SETD8 , SETD8 , KMT5A, KMT5A, KMT5A , KMT5A , PRSET7, PRSET7, PRSET7 , PRSET7 , SET07, SET07, SET07 , SET07 , SET8, SET8, SET8 , SET8 , N-lysine methyltransferase SETD8, N-lysine methyltransferase SETD8, N-lysine methyltransferase SETD8 , N-lysine methyltransferase SETD8 , H4-K20-HMTase SETD8, H4-K20-HMTase SETD8, H4-K20-HMTase SETD8 , H4-K20-HMTase SETD8 , Histone-lysine N-methyltransferase SETD8, Histone-lysine N-methyltransferase SETD8, Histone-lysine N-methyltransferase SETD8 , Histone-lysine N-methyltransferase SETD8 , Lysine N-methyltransferase 5A, Lysine N-methyltransferase 5A, Lysine N-methyltransferase 5A , Lysine N-methyltransferase 5A , PR/SET domain-containing protein 07, PR/SET domain-containing protein 07, PR/SET domain
Gene, Accession #UniProt: Q9NQR1
Catalog #abx026503
Priceplease inquire
Order / More InfoPR/SET Domain-Containing Protein 07 (SET07) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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