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Antigenic Specificity | PR/SET Domain-Containing Protein 07 (SET07) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SET07 is a histone methyltransferase that methylates Lys-20 of histone H4. H4 Lys-20 methylation represents a specific tag for epigenetic transcriptional repression. The nuclear SET07 protein, which associates with silent chromatin on euchromatic arms but shows no association with constitutive heterochromatin, prefers nucleosomes as substrate compared to free histones. It appears that SET07 may play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail. Although the SET domain contains the active site of enzymatic activity, both sequences upstream and downstream of the SET domain are required for methyltransferase activity. |
Immunogen | KLH-conjugated synthetic peptide between 362-393 amino acids from the C-terminal region of human SET07. |
Other Names | SETD8, KMT5A, PRSET7, SET07, SET8, N-lysine methyltransferase SETD8, H4-K20-HMTase SETD8, Histone-lysine N-methyltransferase SETD8, Lysine N-methyltransferase 5A, PR/SET domain-containing protein 07, SET domain-containing protein 8, SETD8, SETD8, SETD8 , SETD8 , KMT5A, KMT5A, KMT5A , KMT5A , PRSET7, PRSET7, PRSET7 , PRSET7 , SET07, SET07, SET07 , SET07 , SET8, SET8, SET8 , SET8 , N-lysine methyltransferase SETD8, N-lysine methyltransferase SETD8, N-lysine methyltransferase SETD8 , N-lysine methyltransferase SETD8 , H4-K20-HMTase SETD8, H4-K20-HMTase SETD8, H4-K20-HMTase SETD8 , H4-K20-HMTase SETD8 , Histone-lysine N-methyltransferase SETD8, Histone-lysine N-methyltransferase SETD8, Histone-lysine N-methyltransferase SETD8 , Histone-lysine N-methyltransferase SETD8 , Lysine N-methyltransferase 5A, Lysine N-methyltransferase 5A, Lysine N-methyltransferase 5A , Lysine N-methyltransferase 5A , PR/SET domain-containing protein 07, PR/SET domain-containing protein 07, PR/SET domain |
Gene, Accession # | UniProt: Q9NQR1 |
Catalog # | abx026503 |
Price | please inquire |
Order / More Info | PR/SET Domain-Containing Protein 07 (SET07) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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