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Antigenic Specificity | SARS-CoV-2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 50 µl, 100 µl, |
Concentration | 0.33 mg/ml |
Applications | ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) NSP1 antibody is a Rabbit polyclonal antibody for the detection of SARS-CoV-2 NSP1. The Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) is an enveloped, positive-stranded RNA viruses that can cause a severe respiratory disease. Its genome consists of a ?30 kb linear, non-segmented, capped, polycistronic, polyadenylated RNA molecule, the first two-third of which is directly translated into two large polyproteins. These two polypeptides are processed into 16 non-structural proteins (nsps), forming the replicase complex, which is active in the cytoplasm in close association with cellular membranes. Nsp1 was proved to be able to suppress host gene expression by promoting host mRNA degradation and was involved in cellular chemokine deregulation. This virus evades the host innate immune response in part through the expression of its non-structural protein (nsp) 1, which inhibits both host gene expression and virus- and interferon (IFN)-dependent signaling. Thus, nsp1 is a promising target for drugs, as inhibition of nsp1 would make SARS-CoV more susceptible to the host antiviral defenses. |
Immunogen | Recombinant SARS-CoV-2 NSP1 (Met1-Gly180) |
Other Names | Severe Acute Respiratory Syndrome Coronavirus 2, SARS-CoV-2, COVID-19, 2019-nCoV, 2019 novel coronavirus, COVID19, Severe Acute Respiratory Syndrome Coronavirus 2, Severe Acute Respiratory Syndrome Coronavirus 2, Severe Acute Respiratory Syndrome Coronavirus 2 , Severe Acute Respiratory Syndrome Coronavirus 2 , SARS-CoV-2, SARS-CoV-2, SARS-CoV-2 , SARS-CoV-2 , COVID-19, COVID-19, COVID-19 , COVID-19 , 2019-nCoV, 2019-nCoV, 2019-nCoV , 2019-nCoV , 2019 novel coronavirus, 2019 novel coronavirus, 2019 novel coronavirus , 2019 novel coronavirus , COVID19, COVID19, COVID19 , COVID19 |
Gene, Accession # | n/a |
Catalog # | abx229989 |
Price | please inquire |
Order / More Info | SARS-CoV-2 Antibody from ABBEXA LTD |
Product Specific References | n/a |
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