Integrin Beta 1 (ITGB1) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Integrin Beta 1 (ITGB1) antibody, protein, ELISA kits.
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| Antigenic Specificity | Integrin Beta 1 (ITGB1) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform beta-1B interferes with isoform beta-1A resulting in a dominant negative effect on cell adhesion and migration (in vitro). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and GNB2L1/RACK1, serves as a platform for SRC activation or inactivation. Plays a mechanistic adhesive role during telophase, required for the successful completion of cytokinesis. |
| Immunogen | Purified His-tagged Human ITGB1 protein |
| Other Names | CD29, Fibronectin receptor beta subunit, FNRB, integrin beta-1, Integrin beta-1 precursor, Integrin VLA-4 beta subunit, ITB1, MDF2, VLAB, GPIIA, MSK12, VLA-BETA, Fibronectin receptor subunit beta, VLA-4 subunit beta, integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12), ITGB1, itgb1-, CD29, CD29, CD29 , CD29 , Fibronectin receptor beta subunit, Fibronectin receptor beta subunit, Fibronectin receptor beta subunit , Fibronectin receptor beta subunit , FNRB, FNRB, FNRB , FNRB , integrin beta-1, integrin beta-1, integrin beta-1 , integrin beta-1 , Integrin beta-1 precursor, Integrin beta-1 precursor, Integrin beta-1 precursor , Integrin beta-1 precursor , Integrin VLA-4 beta subunit, Integrin VLA-4 beta subunit, Integrin VLA-4 beta subunit , Integrin VLA-4 beta subunit , ITB1, ITB1, ITB1 , ITB1 , MDF2, MDF2, MDF2 , MDF2 , VLAB, VLAB, VLAB , VLAB , GPIIA, GPIIA, GPIIA , GPIIA , MSK12, MSK12, MSK12 , MSK12 , VLA-BETA, VLA-BETA, VLA-BETA , V |
| Gene, Accession # | NCBI: NP_002202.2, NP_391988.1, NP_596867.1, UniProt: P05556 |
| Catalog # | abx034994 |
| Price | please inquire |
| Order / More Info | Integrin Beta 1 (ITGB1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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