Granulin (GRN) Antibody from ABBEXA LTD

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Antigenic SpecificityGranulin (GRN)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size20 µl, 50 µl, 100 µl, 200 µl
Concentration> 0.5 mg/ml
ApplicationsWB
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DescriptionGRN antibody is a Rabbit polyclonal antibody against GRN. Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.
ImmunogenRecombinant protein of human GRN.
Other NamesGEP, GP88, PEPI, PGRN, CLN11, PCDGF, Granulins, Glycoprotein of 88 Kda, Progranulin, Granulin G, Granulin F, Granulin B, Granulin A, Granulin C, Granulin D, Granulin E, GRN, Acrogranin, Epithelin precursor, Granulin, Granulin-epithelin, PC cell-derived growth factor, Proepithelin, Paragranulin, Granulin-1, Granulin-2, Granulin-3, Granulin-4, Granulin-5, Granulin-6, Granulin-7, GEP, GEP, GEP , GEP , GP88, GP88, GP88 , GP88 , PEPI, PEPI, PEPI , PEPI , PGRN, PGRN, PGRN , PGRN , CLN11, CLN11, CLN11 , CLN11 , PCDGF, PCDGF, PCDGF , PCDGF , Granulins, Granulins, Granulins , Granulins , Glycoprotein of 88 Kda, Glycoprotein of 88 Kda, Glycoprotein of 88 Kda , Glycoprotein of 88 Kda , Progranulin, Progranulin, Progranulin , Progranulin , Granulin G, Granulin G, Granulin G , Granulin G , Granulin F, Granulin F, Granulin F , Granulin F , Granulin B, Granulin B, Granulin B , Granulin B , Granulin A, Granulin A, Granulin A , Granulin A , Granulin C, Granulin C, Granulin C , Granulin C
Gene, Accession #GRN, Gene ID: 2896, UniProt: P28799
Catalog #abx004421
Priceplease inquire
Order / More InfoGranulin (GRN) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

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