Edit |   |
---|---|
Antigenic Specificity | Cathepsin B (CATB) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein CATB is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. |
Immunogen | KLH-conjugated synthetic peptide between 198-227 amino acids from the Central region of human CATB. |
Other Names | CTSB, CPSB, Cathepsin B, APP secretase, Cathepsin B1, Cathepsin B light chain, Cathepsin B heavy chain, CTSB, CTSB, CTSB , CTSB , CPSB, CPSB, CPSB , CPSB , Cathepsin B, Cathepsin B, Cathepsin B , Cathepsin B , APP secretase, APP secretase, APP secretase , APP secretase , Cathepsin B1, Cathepsin B1, Cathepsin B1 , Cathepsin B1 , Cathepsin B light chain, Cathepsin B light chain, Cathepsin B light chain , Cathepsin B light chain , Cathepsin B heavy chain, Cathepsin B heavy chain, Cathepsin B heavy chain , Cathepsin B heavy chain |
Gene, Accession # | UniProt: P07858 |
Catalog # | abx033357 |
Price | please inquire |
Order / More Info | Cathepsin B (CATB) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950