MAP2 (pS1539) Antibody from ABBEXA LTD

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Antigenic SpecificityMAP2 (pS1539)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, DB
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DescriptionMAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2; two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent. Between postnatal days 10 and 20, MAP2a appears. At the same time, the level of MAP2c drops by 10-fold. This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology. MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats. There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types. MAP2 is known to promote microtubule assembly and to form side-arms on microtubules. It also interacts with neurofilaments, actin, and other elements of the cytoskeleton.
ImmunogenKLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1539 of human MAP2.
Other NamesDKFZp686I2148, MAP2A, MAP2B, MAP2C, MAP 2, MAP-2, microtubule-associated protein 2, MTAP2, MAP2, Microtubule associated protein 2, DKFZp686I2148, DKFZp686I2148, DKFZp686I2148 , DKFZp686I2148 , MAP2A, MAP2A, MAP2A , MAP2A , MAP2B, MAP2B, MAP2B , MAP2B , MAP2C, MAP2C, MAP2C , MAP2C , MAP 2, MAP 2, MAP 2 , MAP 2 , MAP-2, MAP-2, MAP-2 , MAP-2 , microtubule-associated protein 2, microtubule-associated protein 2, microtubule-associated protein 2 , microtubule-associated protein 2 , MTAP2, MTAP2, MTAP2 , MTAP2 , MAP2, MAP2, MAP2 , MAP2 , Microtubule associated protein 2, Microtubule associated protein 2, Microtubule associated protein 2 , Microtubule associated protein 2
Gene, Accession #UniProt: P11137
Catalog #abx032066
Priceplease inquire
Order / More InfoMAP2 (pS1539) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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