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Antigenic Specificity | TNFR (pS274) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | A member of the TNF-receptor superfamily, this protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. |
Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S274 of human TNFR. |
Other Names | Tumor necrosis factor receptor superfamily member 1A, p60, TNF-R1, TNF-RI, TNFR-I, p55, CD120a antigen, TNFRSF1A, TNFAR, TNFR1, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor superfamily member 1A , Tumor necrosis factor receptor superfamily member 1A , p60, p60, p60 , p60 , TNF-R1, TNF-R1, TNF-R1 , TNF-R1 , TNF-RI, TNF-RI, TNF-RI , TNF-RI , TNFR-I, TNFR-I, TNFR-I , TNFR-I , p55, p55, p55 , p55 , CD120a antigen, CD120a antigen, CD120a antigen , CD120a antigen , TNFRSF1A, TNFRSF1A, TNFRSF1A , TNFRSF1A , TNFAR, TNFAR, TNFAR , TNFAR , TNFR1, TNFR1, TNFR1 , TNFR1 |
Gene, Accession # | UniProt: P19438 |
Catalog # | abx031924 |
Price | please inquire |
Order / More Info | TNFR (pS274) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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