Polyadenylate-Binding Protein 2 (PABPN1) Antibody from ABBEXA LTD

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Antigenic SpecificityPolyadenylate-Binding Protein 2 (PABPN1)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl,
Concentrationn/a
ApplicationsELISA, WB
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DescriptionThis gene encodes an abundant nuclear protein that binds with high affinity to nascent poly (A) tails. The protein is required for progressive and efficient polymerization of poly (A) tails on the 3' ends of eukaryotic genes and controls the size of the poly (A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly (A) binding protein is localized in the cytoplasm. An expansion of the trinucleotide (GCG) repeat from normal 6 to 8-13 at the 5' end of the coding region of this gene leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Multiple splice variants have been described but their full-length nature is not known. One splice variant includes introns 1 and 6 but no protein is formed.
ImmunogenKLH-conjugated synthetic peptide between 270-298 amino acids from the C-terminal region of human PABPN1.
Other NamesOPMD, PAB2, PABII, PABP2, PABP-2, PABPN1, Polyadenylate-binding protein 2, Nuclear poly (A) binding protein 1, Poly (A) binding protein II, Polyadenylate-binding nuclear protein 1, Poly (A)-binding protein 2, Poly (A) binding protein 2, Poly (A)-binding protein II, OPMD, OPMD, OPMD , OPMD , PAB2, PAB2, PAB2 , PAB2 , PABII, PABII, PABII , PABII , PABP2, PABP2, PABP2 , PABP2 , PABP-2, PABP-2, PABP-2 , PABP-2 , PABPN1, PABPN1, PABPN1 , PABPN1 , Polyadenylate-binding protein 2, Polyadenylate-binding protein 2, Polyadenylate-binding protein 2 , Polyadenylate-binding protein 2 , Nuclear poly (A) binding protein 1, Nuclear poly (A) binding protein 1, Nuclear poly (A) binding protein 1 , Nuclear poly (A) binding protein 1 , Poly (A) binding protein II, Poly (A) binding protein II, Poly (A) binding protein II , Poly (A) binding protein II , Polyadenylate-binding nuclear protein 1, Polyadenylate-binding nuclear protein 1, Polyadenylate-binding nuclear protein 1 , Polyadenylate-binding
Gene, Accession #PABPN1, UniProt: Q86U42
Catalog #abx029099
Priceplease inquire
Order / More InfoPolyadenylate-Binding Protein 2 (PABPN1) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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