Edit |   |
---|---|
Antigenic Specificity | BH3-Interacting Domain-Containing Protein 3 (Hrk) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein G purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X (L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 homology domain-3 (BH3) motif of BIK. HRK interacts with BCL2 and BCLXL via the BH3 domain, but not with the death-promoting BCL2-related proteins BAX, BAK, or BCLXS. HRK localizes to membranes of intracellular organelles in a pattern similar to that previously reported for BCL2 and BCLXL. |
Immunogen | KLH-conjugated synthetic peptide between 15-50 amino acids from human Hrk BH3 Domain. |
Other Names | HRK, BID3, Activator of apoptosis harakiri, BH3-interacting domain-containing protein 3, Neuronal death protein DP5, HRK, HRK, HRK , HRK , BID3, BID3, BID3 , BID3 , Activator of apoptosis harakiri, Activator of apoptosis harakiri, Activator of apoptosis harakiri , Activator of apoptosis harakiri , BH3-interacting domain-containing protein 3, BH3-interacting domain-containing protein 3, BH3-interacting domain-containing protein 3 , BH3-interacting domain-containing protein 3 , Neuronal death protein DP5, Neuronal death protein DP5, Neuronal death protein DP5 , Neuronal death protein DP5 |
Gene, Accession # | UniProt: O00198 |
Catalog # | abx027221 |
Price | please inquire |
Order / More Info | BH3-Interacting Domain-Containing Protein 3 (Hrk) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950