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Antigenic Specificity | Ubiquitin-Like-Conjugating Enzyme ATG3 (ATG3) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG3L is an E2-like conjugating enzyme facilitating covalent binding of APG8 (MAP1LC3) to phosphatidylethanolamine (PE). APG7 (an E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with APG3. Formation of the PE conjugate is essential for autophagy. |
Immunogen | KLH-conjugated synthetic peptide between 168-197 amino acids from the C-terminal region of human ATG3. |
Other Names | ATG3, Autophagy Related 3, PC3-96, APG3L, Ubiquitin-Like-Conjugating Enzyme ATG3, Autophagy-Related Protein 3, DKFZp564M1178, FLJ22125, MGC15201, HApg3, APG3 3 4, ATG3 Autophagy Related 3 Homolog (S. Cerevisiae), APG3 Autophagy 3-Like (S. Cerevisiae), ATG3 Autophagy Related 3 Homolog, APG3 Autophagy 3-Like, Protein PC3-96, EC 2.3.2.-, APG3-Like, ATG3, ATG3, ATG3 , ATG3 , Autophagy Related 3, Autophagy Related 3, Autophagy Related 3 , Autophagy Related 3 , PC3-96, PC3-96, PC3-96 , PC3-96 , APG3L, APG3L, APG3L , APG3L , Ubiquitin-Like-Conjugating Enzyme ATG3, Ubiquitin-Like-Conjugating Enzyme ATG3, Ubiquitin-Like-Conjugating Enzyme ATG3 , Ubiquitin-Like-Conjugating Enzyme ATG3 , Autophagy-Related Protein 3, Autophagy-Related Protein 3, Autophagy-Related Protein 3 , Autophagy-Related Protein 3 , DKFZp564M1178, DKFZp564M1178, DKFZp564M1178 , DKFZp564M1178 , FLJ22125, FLJ22125, FLJ22125 , FLJ22125 , MGC15201, MGC15201, MGC15201 , MGC15201 , HApg3, HApg3, HApg3 , HApg3 , APG3 3 4, |
Gene, Accession # | ATG3, Gene ID: 64422, NCBI: NP_001265641.1, NP_071933.2, UniProt: Q9NT62 |
Catalog # | abx029992 |
Price | please inquire |
Order / More Info | Ubiquitin-Like-Conjugating Enzyme ATG3 (ATG3) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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