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Antigenic Specificity | Integral Membrane Protein 2C (ITM2C) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity). |
Immunogen | KLH-conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human ITM2C. |
Other Names | E25, BRI3, E25C, ITM3, BRICD2C, ITM2C, Integral membrane protein 2C, Cerebral protein 14, Transmembrane protein BRI3, CT-BRI3, E25, E25, E25 , E25 , BRI3, BRI3, BRI3 , BRI3 , E25C, E25C, E25C , E25C , ITM3, ITM3, ITM3 , ITM3 , BRICD2C, BRICD2C, BRICD2C , BRICD2C , ITM2C, ITM2C, ITM2C , ITM2C , Integral membrane protein 2C, Integral membrane protein 2C, Integral membrane protein 2C , Integral membrane protein 2C , Cerebral protein 14, Cerebral protein 14, Cerebral protein 14 , Cerebral protein 14 , Transmembrane protein BRI3, Transmembrane protein BRI3, Transmembrane protein BRI3 , Transmembrane protein BRI3 , CT-BRI3, CT-BRI3, CT-BRI3 , CT-BRI3 |
Gene, Accession # | ITM2C, UniProt: Q9NQX7 |
Catalog # | abx029346 |
Price | please inquire |
Order / More Info | Integral Membrane Protein 2C (ITM2C) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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