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Antigenic Specificity | Voltage-Dependent Anion-Selective Channel Protein 1 (VDAC1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, IHC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | VDAC1 forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. The protein may participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis. |
Immunogen | KLH-conjugated synthetic peptide between 95-124 amino acids from the Central region of human VDAC1. |
Other Names | VDAC1, VDAC, Voltage-dependent anion-selective channel protein 1, Outer mitochondrial membrane protein porin 1, Plasmalemmal porin, Porin 31HL, Porin 31HM, MGC111064, PORIN, PORIN-31-HL, VDAC1, VDAC1, VDAC1 , VDAC1 , VDAC, VDAC, VDAC , VDAC , Voltage-dependent anion-selective channel protein 1, Voltage-dependent anion-selective channel protein 1, Voltage-dependent anion-selective channel protein 1 , Voltage-dependent anion-selective channel protein 1 , Outer mitochondrial membrane protein porin 1, Outer mitochondrial membrane protein porin 1, Outer mitochondrial membrane protein porin 1 , Outer mitochondrial membrane protein porin 1 , Plasmalemmal porin, Plasmalemmal porin, Plasmalemmal porin , Plasmalemmal porin , Porin 31HL, Porin 31HL, Porin 31HL , Porin 31HL , Porin 31HM, Porin 31HM, Porin 31HM , Porin 31HM , MGC111064, MGC111064, MGC111064 , MGC111064 , PORIN, PORIN, PORIN , PORIN , PORIN-31-HL, PORIN-31-HL, PORIN-31-HL , PORIN-31-HL |
Gene, Accession # | UniProt: P21796 |
Catalog # | abx032902 |
Price | please inquire |
Order / More Info | Voltage-Dependent Anion-Selective Channel Protein 1 (VDAC1) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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