Tumor Necrosis Factor (TNF) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Tumor Necrosis Factor (TNF) antibody, protein, ELISA kits.
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| Antigenic Specificity | Tumor Necrosis Factor (TNF) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TNF antibody is a Rabbit polyclonal antibody against TNF. TNF-?, the prototypical member of the TNF protein superfamily, is a homotrimeric type-II membrane proteinMembrane-bound TNF-? is cleaved by the metalloprotease TACE/ADAM17 to geneRate a soluble homotrimerBoth membrane and soluble forms of TNF-? are biologically activeTNF-? is produced by a variety of immune cells including T cells, B cells, NK cells, and macrophagesCellular response to TNF-? is mediated through interaction with receptors TNF-R1 and TNF-R2 and results in activation of pathways that favor both cell survival and apoptosis depending on the cell type and biological contextActivation of kinase pathways (including JNK, Erk (p44/42), p38 MAPK, and NF-?B) promotes the survival of cells, while TNF-?-mediated activation of caspase-8 leads to programmed cell deathTNF-? plays a key regulatory role in inflammation and host defense against bacterial infection, notably Mycobacterium tuberculosisThe role of TNF-? in autoimmunity is underscored by blocking TNF-? action to treat rheumatoid arthritis and Crohn's diseaseThis protein is involved in Immunology. |
| Immunogen | C term -peptide of human SFPQ. |
| Other Names | TNF, Tumor Necrosis Factor, Tumour Necrosis Factor, TNF-Alpha, TNF Alpha, TNFSF2, TNFA, DIF, Tumor Necrosis Factor Ligand Superfamily Member 2, Tumour Necrosis Factor Ligand Superfamily Member 2, TNF-A, TNF A, Tumor Necrosis Factor (TNF Superfamily, Member 2, Tumour Necrosis Factor (TNF Superfamily, Member 2, Tumor Necrosis Factor Ligand 1F, Tumour Necrosis Factor Ligand 1F, Tumor Necrosis Factor-Alpha, Tumour Necrosis Factor-Alpha, Tumor Necrotic Factor Alpha, Tumour Necrosis Factor Alpha, TNF Superfamily, Member 2, TNF, Macrophage-Derived, TNF, Monocyte-Derived, APC1 Protein, Cachectin, Cachexin, TNLG1F, TNF, TNF , TNF-, TNF, TNF, TNF , TNF , Tumor Necrosis Factor, Tumor Necrosis Factor, Tumor Necrosis Factor , Tumor Necrosis Factor , Tumour Necrosis Factor, Tumour Necrosis Factor, Tumour Necrosis Factor , Tumour Necrosis Factor , TNF-Alpha, TNF-Alpha, TNF-Alpha , TNF-Alpha , TNF Alpha, TNF Alpha, TNF Alpha , TNF Alpha , TNFSF2, TNFSF2, TNFSF2 , TNFSF2 , TNFA, TNFA, TNFA , |
| Gene, Accession # | TNF, Gene ID: 7124, UniProt: P01375 |
| Catalog # | abx117001 |
| Price | please inquire |
| Order / More Info | Tumor Necrosis Factor (TNF) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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