Middle East Respiratory Syndrome Spike (MERS-CoV S) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Middle East Respiratory Syndrome Spike (MERS-CoV S) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Middle East Respiratory Syndrome Spike (MERS-CoV S) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 50 µl, 100 µl, |
| Concentration | 1 mg/ml |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Middle East Respiratory Syndrome Spike (MERS-CoV S) antibody is a Rabbit polyclonal antibody for the detection of Middle East Respiratory Syndrome Spike (MERS-CoV S). The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of heterologous proteins on the virus surface that function together. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. It's been reported that SARS-CoV-2 (COVID-19 coronavirus, 2019-nCoV) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate. |
| Immunogen | Recombinant MERS-CoV Spike Protein (S1+S2 ECD, aa 1-1297) |
| Other Names | MERS-CoV S, MERS-CoV S1, MERS-CoV Spike Protein, MERS-CoV Spike Glyoprotein, Middle East Respiratory Syndrome Spike Protein, Middle East Respiratory Syndrome Spike Glycoprotein, MERS-CoV RBD, MERS-CoV Spike RBD, Middle East Respiratory Syndrome Spike RBD, MERS-CoV S, MERS-CoV S, MERS-CoV S , MERS-CoV S , MERS-CoV S1, MERS-CoV S1, MERS-CoV S1 , MERS-CoV S1 , MERS-CoV Spike Protein, MERS-CoV Spike Protein, MERS-CoV Spike Protein , MERS-CoV Spike Protein , MERS-CoV Spike Glyoprotein, MERS-CoV Spike Glyoprotein, MERS-CoV Spike Glyoprotein , MERS-CoV Spike Glyoprotein , Middle East Respiratory Syndrome Spike Protein, Middle East Respiratory Syndrome Spike Protein, Middle East Respiratory Syndrome Spike Protein , Middle East Respiratory Syndrome Spike Protein , Middle East Respiratory Syndrome Spike Glycoprotein, Middle East Respiratory Syndrome Spike Glycoprotein, Middle East Respiratory Syndrome Spike Glycoprotein , Middle East Respiratory Syndrome Spike Glycoprotein , MERS-CoV RBD, |
| Gene, Accession # | n/a |
| Catalog # | abx201383 |
| Price | please inquire |
| Order / More Info | Middle East Respiratory Syndrome Spike (MERS-CoV S) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950
Customer Service: info@abbexa.com
Technical Support: support@abbexa.com
Orders: orders@abbexa.com
https://www.abbexa.com
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950
Profile of ABBEXA LTD
Return to Antibodies