Edit |   |
---|---|
Antigenic Specificity | Fibrillarin (FBL) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FBL is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. This protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. |
Immunogen | KLH-conjugated synthetic peptide between 105-135 amino acids from the Central region of human FBL. |
Other Names | FBL, FIB, FLRN, RNU3IP1, FIB1, rRNA 2'-O-methyltransferase fibrillarin, 34 kDa nucleolar scleroderma antigen, FBL, FBL, FBL , FBL , FIB, FIB, FIB , FIB , FLRN, FLRN, FLRN , FLRN , RNU3IP1, RNU3IP1, RNU3IP1 , RNU3IP1 , FIB1, FIB1, FIB1 , FIB1 , rRNA 2'-O-methyltransferase fibrillarin, rRNA 2'-O-methyltransferase fibrillarin, rRNA 2'-O-methyltransferase fibrillarin , rRNA 2'-O-methyltransferase fibrillarin , 34 kDa nucleolar scleroderma antigen, 34 kDa nucleolar scleroderma antigen, 34 kDa nucleolar scleroderma antigen , 34 kDa nucleolar scleroderma antigen |
Gene, Accession # | UniProt: P22087 |
Catalog # | abx031701 |
Price | please inquire |
Order / More Info | Fibrillarin (FBL) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950