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Antigenic Specificity | Toll Like Receptor 4 (TLR4) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. |
Immunogen | KLH-conjugated synthetic peptide between 669-698 amino acids from the Central region of human TLR4. |
Other Names | TLR4, TLR-4, Toll-like receptor 4, hToll, CD284, TOLL, ARMD10, TLR4, TLR4, TLR4 , TLR4 , TLR-4, TLR-4, TLR-4 , TLR-4 , Toll-like receptor 4, Toll-like receptor 4, Toll-like receptor 4 , Toll-like receptor 4 , hToll, hToll, hToll , hToll , CD284, CD284, CD284 , CD284 , TOLL, TOLL, TOLL , TOLL , ARMD10, ARMD10, ARMD10 , ARMD10 |
Gene, Accession # | TLR4, UniProt: O00206 |
Catalog # | abx034472 |
Price | please inquire |
Order / More Info | Toll Like Receptor 4 (TLR4) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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