Signal Transducer And Activator of Transcription 1 Phospho-Tyr701 (STAT1 pY701) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Signal Transducer And Activator of Transcription 1 Phospho-Tyr701 (STAT1 pY701) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Signal Transducer And Activator of Transcription 1 Phospho-Tyr701 (STAT1 pY701) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | STAT1 (pY701) antibody is a Rabbit polyclonal antibody against STAT1 (pY701). Signal transducer and activator of transcription that mediates signaling by interferons (IFNs). Following type I IFN (IFN-a and IFN-beta) binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. |
| Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y701 of human STAT1. |
| Other Names | DKFZp686B04100, ISGF-3, signal transducer and activator of transcription 1, 91kDa, Signal transducer and activator of transcription 1-alpha/beta, signal transducer and activator of transcription-1, STAT1, STAT91, Transcription factor ISGF-3 components p91/p84, stat1-, DKFZp686B04100, DKFZp686B04100, DKFZp686B04100 , DKFZp686B04100 , ISGF-3, ISGF-3, ISGF-3 , ISGF-3 , signal transducer and activator of transcription 1, signal transducer and activator of transcription 1, signal transducer and activator of transcription 1 , signal transducer and activator of transcription 1 , 91kDa, 91kDa, 91kDa , 91kDa , Signal transducer and activator of transcription 1-alpha/beta, Signal transducer and activator of transcription 1-alpha/beta, Signal transducer and activator of transcription 1-alpha/beta , Signal transducer and activator of transcription 1-alpha/beta , signal transducer and activator of transcription-1, signal transducer and activator of transcription-1, signal transducer and activ |
| Gene, Accession # | STAT1, Gene ID: 6772, UniProt: P42224 |
| Catalog # | abx000187 |
| Price | please inquire |
| Order / More Info | Signal Transducer And Activator of Transcription 1 Phospho-Tyr701 (STAT1 pY701) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950
Customer Service: info@abbexa.com
Technical Support: support@abbexa.com
Orders: orders@abbexa.com
https://www.abbexa.com
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950
Profile of ABBEXA LTD
Return to Antibodies