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Antigenic Specificity | Wolf-Hirschhorn Syndrome Candidate 2 Protein (WHSC2) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG2b |
Format | Protein G purified |
Size | 100 µl, |
Concentration | 1 mg/ml |
Applications | ELISA, WB, IHC, IF/ICC, FCM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene is expressed ubiquitously with higher levels in fetal than in adult tissues.It encodes a protein sharing 93% sequence identity with the mouse protein.Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4.This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome.The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients.This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. |
Immunogen | Purified recombinant fragment of human WHSC2 (AA: 280-511) expressed in E. coli. |
Other Names | WHSC2, NELFA, Negative elongation factor A, Wolf-Hirschhorn syndrome candidate 2 protein, NELF-A, P/OKcl.15, WHSC2, WHSC2, WHSC2 , WHSC2 , NELFA, NELFA, NELFA , NELFA , Negative elongation factor A, Negative elongation factor A, Negative elongation factor A , Negative elongation factor A , Wolf-Hirschhorn syndrome candidate 2 protein, Wolf-Hirschhorn syndrome candidate 2 protein, Wolf-Hirschhorn syndrome candidate 2 protein , Wolf-Hirschhorn syndrome candidate 2 protein , NELF-A, NELF-A, NELF-A , NELF-A , P/OKcl.15, P/OKcl.15, P/OKcl.15 , P/OKcl.15 |
Gene, Accession # | Gene ID: 7469 |
Catalog # | abx016021 |
Price | please inquire |
Order / More Info | Wolf-Hirschhorn Syndrome Candidate 2 Protein (WHSC2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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