Promyelocytic Leukemia Protein (PML) Antibody from ABBEXA LTD
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| Antigenic Specificity | Promyelocytic Leukemia Protein (PML) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 20 µl, 50 µl, 100 µl, 200 µl |
| Concentration | > 0.5 mg/ml |
| Applications | WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PML antibody is a Rabbit polyclonal antibody against PML. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]. |
| Immunogen | Recombinant protein of human PML. |
| Other Names | MYL, Probable transcription factor PML, TRIM19, Tripartite motif protein 19, RNF71, PP8675, PML, MYL, MYL, MYL , MYL , Probable transcription factor PML, Probable transcription factor PML, Probable transcription factor PML , Probable transcription factor PML , TRIM19, TRIM19, TRIM19 , TRIM19 , Tripartite motif protein 19, Tripartite motif protein 19, Tripartite motif protein 19 , Tripartite motif protein 19 , RNF71, RNF71, RNF71 , RNF71 , PP8675, PP8675, PP8675 , PP8675 , PML, PML, PML , PML |
| Gene, Accession # | PML, Gene ID: 5371, UniProt: P29590 |
| Catalog # | abx001098 |
| Price | please inquire |
| Order / More Info | Promyelocytic Leukemia Protein (PML) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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