Serine/Threonine-Protein Kinase MARK1 (MARK1) Antibody from ABBEXA LTD
Search, find, compare suppliers for anti-Serine/Threonine-Protein Kinase MARK1 (MARK1) antibody, protein, ELISA kits.
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| Antigenic Specificity | Serine/Threonine-Protein Kinase MARK1 (MARK1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | MARK is a family of kinases that is known for its involvement in establishing cell polarity and in phosphorylating tau protein during Alzheimer neurodegeneration. Expression of MARK causes the phosphorylation of MAPs at their KXGS motifs, thereby detaching MAPs from the microtubules and thus facilitating the transport of particles. This occurs without impairing the intrinsic activity of motors because the velocity during active movement remains unchanged. In primary retinal ganglion cells, transfection with tau leads to the inhibition of axonal transport of mitochondria, APP vesicles, and other cell components which leads to starvation of axons and vulnerability against stress. This transport inhibition can be rescued by phosphorylating tau with MARK. |
| Immunogen | KLH-conjugated synthetic peptide between 671-700 amino acids from the C-terminal region of human MARK1. |
| Other Names | MARK1, KIAA1477, MARK, Serine/threonine-protein kinase MARK1, MAP/microtubule affinity-regulating kinase 1, PAR1 homolog c, AW491150, B930025N23Rik, Emk3, mKIAA1477, Par-1c, Par1c, MARK1, MARK1, MARK1 , MARK1 , KIAA1477, KIAA1477, KIAA1477 , KIAA1477 , MARK, MARK, MARK , MARK , Serine/threonine-protein kinase MARK1, Serine/threonine-protein kinase MARK1, Serine/threonine-protein kinase MARK1 , Serine/threonine-protein kinase MARK1 , MAP/microtubule affinity-regulating kinase 1, MAP/microtubule affinity-regulating kinase 1, MAP/microtubule affinity-regulating kinase 1 , MAP/microtubule affinity-regulating kinase 1 , PAR1 homolog c, PAR1 homolog c, PAR1 homolog c , PAR1 homolog c , AW491150, AW491150, AW491150 , AW491150 , B930025N23Rik, B930025N23Rik, B930025N23Rik , B930025N23Rik , Emk3, Emk3, Emk3 , Emk3 , mKIAA1477, mKIAA1477, mKIAA1477 , mKIAA1477 , Par-1c, Par-1c, Par-1c , Par-1c , Par1c, Par1c, Par1c , Par1c |
| Gene, Accession # | NCBI: NP_061120.3, UniProt: Q9P0L2 |
| Catalog # | abx025119 |
| Price | please inquire |
| Order / More Info | Serine/Threonine-Protein Kinase MARK1 (MARK1) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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