RNA Polymerase III Subunit C (POLR3C) Antibody from ABBEXA LTD
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| Antigenic Specificity | RNA Polymerase III Subunit C (POLR3C) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway. |
| Immunogen | KLH-conjugated synthetic peptide between 202-230 amino acids from the Central region of human POLR3C. |
| Other Names | POLR3C, DNA-directed RNA polymerase III subunit RPC3, DNA-directed RNA polymerase III subunit C, RNA polymerase III 62 kDa subunit, Rna Polymerase Iii Subunit C3, Rpc62, POLR3C, POLR3C, POLR3C , POLR3C , DNA-directed RNA polymerase III subunit RPC3, DNA-directed RNA polymerase III subunit RPC3, DNA-directed RNA polymerase III subunit RPC3 , DNA-directed RNA polymerase III subunit RPC3 , DNA-directed RNA polymerase III subunit C, DNA-directed RNA polymerase III subunit C, DNA-directed RNA polymerase III subunit C , DNA-directed RNA polymerase III subunit C , RNA polymerase III 62 kDa subunit, RNA polymerase III 62 kDa subunit, RNA polymerase III 62 kDa subunit , RNA polymerase III 62 kDa subunit , Rna Polymerase Iii Subunit C3, Rna Polymerase Iii Subunit C3, Rna Polymerase Iii Subunit C3 , Rna Polymerase Iii Subunit C3 , Rpc62, Rpc62, Rpc62 , Rpc62 |
| Gene, Accession # | POLR3C, UniProt: Q9BUI4 |
| Catalog # | abx029368 |
| Price | please inquire |
| Order / More Info | RNA Polymerase III Subunit C (POLR3C) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
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