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Antigenic Specificity | Exoribonuclease 2 / EXOD1 (ERI2) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl, |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | EXOD1 (Exonuclease domain-containing protein 1), also known as ERI2 (ERI1 exoribonuclease 2), is a 691 amino acid protein that contains one exonuclease domain, which catalyzes the hydrolysis of unpaired or mismatched nucleotides. EXOD1 acitivity is dependent on the binding of two magnesium ions per subunit. There are four isoforms of EXOD1 that are produced as a result of alternative splicing events. The gene encoding EXOD1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. |
Immunogen | KLH-conjugated synthetic peptide between 444-472 amino acids from the Central region of human ERI2. |
Other Names | ERI2, EXOD1, KIAA1504, ERI1 exoribonuclease 2, Exonuclease domain-containing protein 1, ERI2, ERI2, ERI2 , ERI2 , EXOD1, EXOD1, EXOD1 , EXOD1 , KIAA1504, KIAA1504, KIAA1504 , KIAA1504 , ERI1 exoribonuclease 2, ERI1 exoribonuclease 2, ERI1 exoribonuclease 2 , ERI1 exoribonuclease 2 , Exonuclease domain-containing protein 1, Exonuclease domain-containing protein 1, Exonuclease domain-containing protein 1 , Exonuclease domain-containing protein 1 |
Gene, Accession # | ERI2, UniProt: A8K979 |
Catalog # | abx028886 |
Price | please inquire |
Order / More Info | Exoribonuclease 2 / EXOD1 (ERI2) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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