Caspase 3 (CASP3) Antibody from ABBEXA LTD
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| Antigenic Specificity | Caspase 3 (CASP3) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 100 µg, |
| Concentration | 2 mg/ml |
| Applications | ELISA, WB, IHC, IF/ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Caspase 3 (CASP3) antibody is a Rabbit polyclonal antibody for the detection of Caspase 3. Caspase 3, also named as CPP32, SCA-1 and Apopain, belongs to the peptidase C14A family. Caspase 3 is involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Caspase 3 cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6,-7 and-9. Caspase 3 is involved in the cleavage of huntingtin. The antibody can recognize p17 and p32 of Caspase 3. |
| Immunogen | caspase 3, apoptosis-related cysteine peptidase |
| Other Names | Apopain precursor, CASP-3, CPP-32, CPP32, Caspase-3, Cysteine protease CPP32, ICE3, SCA-1, SREBP cleavage activity 1, Yama protein, Apopain, CASP3, caspase 3, apoptosis-related cysteine peptidase, apoptosis-related cysteine protease, Caspase-3 subunit p12, Caspase-3 subunit p17, CPP32B, PARP cleavage protease, procaspase3, Protein Yama, Yama, Cysteine Protease Cpp32Protein Yama, caspase 3, apoptosis-related cysteine protease, HGNC:1504, caspase 3, apoptosis-related cysteine peptidase, SCA1, Apoptain, Cysteinyl Aspartate Specific Proteinases 3, Apopain precursor, Apopain precursor, Apopain precursor , Apopain precursor , CASP-3, CASP-3, CASP-3 , CASP-3 , CPP-32, CPP-32, CPP-32 , CPP-32 , CPP32, CPP32, CPP32 , CPP32 , Caspase-3, Caspase-3, Caspase-3 , Caspase-3 , Cysteine protease CPP32, Cysteine protease CPP32, Cysteine protease CPP32 , Cysteine protease CPP32 , ICE3, ICE3, ICE3 , ICE3 , SCA-1, SCA-1, SCA-1 , SCA-1 , SREBP cleavage activity 1, SREBP cleavage activity 1, SREBP c |
| Gene, Accession # | CASP3, Gene ID: 836, UniProt: P42574 |
| Catalog # | abx239969 |
| Price | please inquire |
| Order / More Info | Caspase 3 (CASP3) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
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