RAD51 Recombinase (RAD51) Antibody from ABBEXA LTD

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Antigenic SpecificityRAD51 Recombinase (RAD51)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size100 µg,
Concentration2 mg/ml
ApplicationsELISA, IHC
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DescriptionRAD51 Recombinase (RAD51) antibody is a Rabbit polyclonal antibody for the detection of RAD51.

Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange (PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
ImmunogenRAD51 homolog
Other NamesRAD51A, RECA, RAD51A, RAD51A, RAD51A , RAD51A , RECA, RECA, RECA , RECA
Gene, Accession #RAD51, Gene ID: 5888, UniProt: Q06609
Catalog #abx218152
Priceplease inquire
Order / More InfoRAD51 Recombinase (RAD51) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
181 Cambridge Science Park
Cambridge, CB4 0GJ UK
P: +44 (0) 1223 755950

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