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Antigenic Specificity | Gamma-Crystallin D (CRYGD) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CRYGD antibody is a Rabbit polyclonal antibody against CRYGD. Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. |
Immunogen | Recombinant protein of human CRYGD. |
Other Names | CCP, PCC, CACA, CCA3, CRYG4, CTRCT4, cry-g-D, CRYGD, Gamma-crystallin D, Gamma-D-crystallin, Gamma-crystallin 4, CCP, CCP, CCP , CCP , PCC, PCC, PCC , PCC , CACA, CACA, CACA , CACA , CCA3, CCA3, CCA3 , CCA3 , CRYG4, CRYG4, CRYG4 , CRYG4 , CTRCT4, CTRCT4, CTRCT4 , CTRCT4 , cry-g-D, cry-g-D, cry-g-D , cry-g-D , CRYGD, CRYGD, CRYGD , CRYGD , Gamma-crystallin D, Gamma-crystallin D, Gamma-crystallin D , Gamma-crystallin D , Gamma-D-crystallin, Gamma-D-crystallin, Gamma-D-crystallin , Gamma-D-crystallin , Gamma-crystallin 4, Gamma-crystallin 4, Gamma-crystallin 4 , Gamma-crystallin 4 |
Gene, Accession # | CRYGD, Gene ID: 1421, UniProt: P07320 |
Catalog # | abx004390 |
Price | please inquire |
Order / More Info | Gamma-Crystallin D (CRYGD) Antibody from ABBEXA LTD |
Product Specific References | n/a |
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