Serine/threonine-Protein Kinase Chk1 (CHK1) Antibody from ABBEXA LTD

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Antigenic SpecificitySerine/threonine-Protein Kinase Chk1 (CHK1)
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG1
FormatProtein G purified
Size100 µl,
Concentration1 mg/ml
ApplicationsELISA, WB
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DescriptionCHK1, also known as CHEK1, it is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis.Cdc25, when phosphorylated on serine 216 by CHK1 becomes bound by an adaptor protein in the cytoplasm.Therefore it is inhibited from removing the inhibiting phosphate from MPF (mitotic/maturation promoting factor) added by Wee1.Consequently, a cell is prevented from entering mitosis.CHK1 can also phosphorylate p53 at Ser20 in vitro.
ImmunogenPurified recombinant fragment of CHK1 expressed in E. coli.
Other NamesCheckpoint, S. pombe, homolog of, 1, CHEK1, CHK1, CHK1 checkpoint homolog (S. pombe), Serine/threonine-protein kinase Chk1, kinase Chk1, CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase-1, Checkpoint, Checkpoint, Checkpoint , Checkpoint , S. pombe, S. pombe, S. pombe , S. pombe , homolog of, homolog of, homolog of , homolog of , 1, 1, 1 , 1 , CHEK1, CHEK1, CHEK1 , CHEK1 , CHK1, CHK1, CHK1 , CHK1 , CHK1 checkpoint homolog (S. pombe), CHK1 checkpoint homolog (S. pombe), CHK1 checkpoint homolog (S. pombe) , CHK1 checkpoint homolog (S. pombe) , Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase Chk1 , Serine/threonine-protein kinase Chk1 , kinase Chk1, kinase Chk1, kinase Chk1 , kinase Chk1 , CHK1 checkpoint homolog, CHK1 checkpoint homolog, CHK1 checkpoint homolog , CHK1 checkpoint homolog , Cell cycle checkpoint kinase, Cell cycle checkpoint kinase, Cell cycle checkpoint kinase , Cell cycle checkp
Gene, Accession #Gene ID: 1111
Catalog #abx015730
Priceplease inquire
Order / More InfoSerine/threonine-Protein Kinase Chk1 (CHK1) Antibody from ABBEXA LTD
Product Specific Referencesn/a
ABBEXA LTD
ABBEXA LTD
ABBEXA LTD
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