Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) Antibody from ABBEXA LTD
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| Antigenic Specificity | Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 100 µg, |
| Concentration | 2 mg/ml |
| Applications | ELISA, WB, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) antibody is a Rabbit polyclonal antibody for the detection of MAP3K3. The mitogen-activated protein/ERK kinase kinase 3 (MEKK3) is a member of a family of MEKK/Ste11 serine/threonine protein kinases. One function of MEKK3 is to serve as an upstream regulatory kinase in the mitogen-activated protein kinase cascade, however, it also plays a critical role in other signaling pathways. MEKK3 regulates several important functions including cell survival and proliferation. It is ubiquitously expressed in multiple tissues and has been found in complexes with scaffold proteins and other kinases. (PMID: 18206350).Cerebral cavernous malformations (CCMs) complex regulation of MEKK3 is essential during vertebrate heart development. MEKK3 signalling and KLF2/4 may be targeted to develop new CCM therapeutics. |
| Immunogen | mitogen-activated protein kinase kinase kinase 3 |
| Other Names | MAP3K3, MAPK/ERK kinase kinase 3, MAPKKK3, MEK kinase 3, MEKK 3, MEKK3, MAP3K3, MAP3K3, MAP3K3 , MAP3K3 , MAPK/ERK kinase kinase 3, MAPK/ERK kinase kinase 3, MAPK/ERK kinase kinase 3 , MAPK/ERK kinase kinase 3 , MAPKKK3, MAPKKK3, MAPKKK3 , MAPKKK3 , MEK kinase 3, MEK kinase 3, MEK kinase 3 , MEK kinase 3 , MEKK 3, MEKK 3, MEKK 3 , MEKK 3 , MEKK3, MEKK3, MEKK3 , MEKK3 |
| Gene, Accession # | MAP3K3, Gene ID: 4215, UniProt: Q99759 |
| Catalog # | abx012210 |
| Price | please inquire |
| Order / More Info | Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
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