Caspase 3 (CASP3) Antibody from ABBEXA LTD
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| Antigenic Specificity | Caspase 3 (CASP3) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 80 µl, 400 µl, |
| Concentration | n/a |
| Applications | ELISA, WB, IHC, FCM |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CASP3 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. |
| Immunogen | KLH-conjugated synthetic peptide between 60-90 amino acids from the Central region of human Caspase-3 (CASP3). |
| Other Names | Apopain precursor, CASP-3, CPP-32, CPP32, Caspase-3, Cysteine protease CPP32, ICE3, SCA-1, SREBP cleavage activity 1, Yama protein, Apopain, CASP3, caspase 3, apoptosis-related cysteine peptidase, apoptosis-related cysteine protease, Caspase-3 subunit p12, Caspase-3 subunit p17, CPP32B, PARP cleavage protease, procaspase3, Protein Yama, Yama, Cysteine Protease Cpp32Protein Yama, caspase 3, apoptosis-related cysteine protease, HGNC:1504, caspase 3, apoptosis-related cysteine peptidase, SCA1, Apoptain, Cysteinyl Aspartate Specific Proteinases 3, Apopain precursor, Apopain precursor, Apopain precursor , Apopain precursor , CASP-3, CASP-3, CASP-3 , CASP-3 , CPP-32, CPP-32, CPP-32 , CPP-32 , CPP32, CPP32, CPP32 , CPP32 , Caspase-3, Caspase-3, Caspase-3 , Caspase-3 , Cysteine protease CPP32, Cysteine protease CPP32, Cysteine protease CPP32 , Cysteine protease CPP32 , ICE3, ICE3, ICE3 , ICE3 , SCA-1, SCA-1, SCA-1 , SCA-1 , SREBP cleavage activity 1, SREBP cleavage activity 1, SREBP c |
| Gene, Accession # | UniProt: P42574 |
| Catalog # | abx033479 |
| Price | please inquire |
| Order / More Info | Caspase 3 (CASP3) Antibody from ABBEXA LTD |
| Product Specific References | n/a |
ABBEXA LTD
ABBEXA LTD
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