Edit |   |
---|---|
Antigenic Specificity | Interleukin 6 Receptor (IL6R) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL6R Antibody is a Rabbit Polyclonal antibody against IL6R. Interleukin-6 (IL-6) is a pleiotropic cytokine produced by a variety of cells during infection, trauma, and immunological challenge (PMID: 8274730). IL-6 acts via a receptor complex consisting of two distinct membrane-bound glycoproteins, an 80-kDa IL-6-binding subunit (IL6R, CD126, gp80) and a 130-kDa signal-transducing element (gp130, CD130). After binding of IL-6 to membrane-bound IL6R, the complex of IL-6 and IL6R associates with gp130, thus activating the receptor (PMID: 9716487). Expression of gp130 is found in almost all organs while expression of IL6R is predominantly confined to hepatocytes and leukocyte subpopulations (monocytes, neutrophils, T cells, and B cells) (PMID: 11149892). Soluble form of IL6R has been found in human serum and urine. |
Immunogen | Recombinant protein of human IL6R. |
Other Names | IL6R, Interleukin-6 Receptor, IL6, IL-6, IL-6R, IL 6R, Interleukin 6 Receptor, IL-6 Receptor Subunit Alpha, Membrane Glycoprotein 80, CD126 Antigen, IL-6R 1, IL-6RA, Gp80, IL-6R Subunit Alpha, IL-6R-Alpha, IL-6R-1, CD126, IL6RA, IL6RQ, IL6Q, IL6R, IL6R, IL6R, IL6R, Interleukin-6 Receptor, Interleukin-6 Receptor, Interleukin-6 Receptor, Interleukin-6 Receptor, IL6, IL6, IL6, IL6, IL-6, IL-6, IL-6, IL-6, IL-6R, IL-6R, IL-6R, IL-6R, IL 6R, IL 6R, IL 6R, IL 6R, Interleukin 6 Receptor, Interleukin 6 Receptor, Interleukin 6 Receptor, Interleukin 6 Receptor, IL-6 Receptor Subunit Alpha, IL-6 Receptor Subunit Alpha, IL-6 Receptor Subunit Alpha, IL-6 Receptor Subunit Alpha, Membrane Glycoprotein 80, Membrane Glycoprotein 80, Membrane Glycoprotein 80, Membrane Glycoprotein 80, CD126 Antigen, CD126 Antigen, CD126 Antigen, CD126 Antigen, IL-6R 1, IL-6R 1, IL-6R 1, IL-6R 1, IL-6RA, IL-6RA, IL-6RA, IL-6RA, Gp80, Gp80, Gp80, Gp80, IL-6R Subunit Alpha, IL-6R Subunit Alpha, IL-6R Subunit Alpha, IL-6R Subunit Alpha, IL-6R-Alpha, IL-6R-Alpha, IL-6R-Alpha, IL-6R-Alpha, IL-6R-1, IL-6R-1, IL-6R-1, IL-6R-1, CD126, CD126, CD126, CD126, IL6RA, IL6RA, IL6RA, IL6RA, IL6RQ, IL6RQ, IL6RQ, IL6RQ, IL6Q, IL6Q, IL6Q, IL6Q |
Gene, Accession # | IL6R, Gene ID: 3570, UniProt: P08887 |
Catalog # | abx001321 |
Price | please inquire |
Order / More Info | Interleukin 6 Receptor (IL6R) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950