Edit |   |
---|---|
Antigenic Specificity | Protein SET (SET) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 20 µl, 50 µl, 100 µl, 200 µl |
Concentration | > 0.5 mg/ml |
Applications | WB, IHC, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SET antibody is a Rabbit polyclonal antibody against SET. The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Recombinant protein of human SET. |
Other Names | 2PP2A, IGAAD, TAF-I, I2PP2A, IPP2A2, PHAPII, TAF-IBETA, Protein SET, HLA-DR-associated protein II, Inhibitor of granzyme A-activated DNase, Phosphatase 2A inhibitor I2PP2A, I-2PP2A, Template-activating factor I, SET, SET nuclear oncogene, LA-DR-associated protein II, OTTHUMP00000022286, SET translocation (myeloid leukemia-associated), Template-Activating Factor-I, chromatin remodelling factor, inhibitor of g, 2PP2A, 2PP2A, 2PP2A , 2PP2A , IGAAD, IGAAD, IGAAD , IGAAD , TAF-I, TAF-I, TAF-I , TAF-I , I2PP2A, I2PP2A, I2PP2A , I2PP2A , IPP2A2, IPP2A2, IPP2A2 , IPP2A2 , PHAPII, PHAPII, PHAPII , PHAPII , TAF-IBETA, TAF-IBETA, TAF-IBETA , TAF-IBETA , Protein SET, Protein SET, Protein SET , Protein SET , HLA-DR-associated protein II, HLA-DR-associated protein II, HLA-DR-associated protein II , HLA-DR-associated protein II , Inhibitor of granzyme A-activated DNase, Inhibitor of granzyme A-activated DNase, Inhibitor of granzyme A-activated DNase , Inhibitor of granzyme A-activated DNase |
Gene, Accession # | SET, Gene ID: 6418, UniProt: Q01105 |
Catalog # | abx004747 |
Price | please inquire |
Order / More Info | Protein SET (SET) Antibody from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950