alpha Tubulin Antibody from ANTIBODIES-ONLINE GmbH

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Antigenic Specificityalpha Tubulin
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieschicken, human, mouse, rabbit, rat, zebrafish
Isotypen/a
Formatbiotin conjugate
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA, Western Blotting
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DescriptionAlpha-tubulin belongs to the tubulin superfamily, which is composed of six distinct families. Along with beta-tubulins, alpha-tubulins are the major components of microtubules. These microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Alpha- and beta-tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter (reviewed in 1). Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha-tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase (2). Another post-translational modification of detyrosinated alpha-tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle (3). Like GAPDH and ?-Actin, this antibody makes an excellent loading control in immunoblots. Target Information: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
ImmunogenBiotin-Alpha-tubulin antibody was raised against an 18 amino acid peptide near the carboxy terminus of human alpha-tubulin
Other NamesTuba1|alpha-tubulin 1|tubulin alpha-1 chain|tubulin alpha-1A chain|tubulin|alpha 1|tubulin, alpha 1A|Tuba1a|alpha Tubulin|K-ALPHA-1|alpha-tubulin ubiquitous|tubulin K-alpha-1|tubulin alpha-1B chain|tubulin alpha-ubiquitous chain|alpha|ubiquitous|tubulin alpha 1b|TUBA1B|Tuba-1|Talpha1 alpha-tubulin|alpha-tubulin isotype M-alpha-1|cb944|fb22g06|wu:fb22g06|tubulin alpha-1C chain|tubulin, alpha 1b|Calpha1|Alpha-tubulin I
Gene, Accession #Gene ID: 10376, 373080, 421169, 100009327
Catalog #ABIN6992214
Price$519
Order / More Infoalpha Tubulin Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

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