CD45RA/B Antibody from ANTIBODIES-ONLINE GmbH

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Antigenic SpecificityCD45RA/B
CloneOX-33
Host SpeciesMouse
Reactive Speciesrat
IsotypeIgG1
Formatphycoerythrin (PE) conjugate
Size50 µg
Concentrationn/a
ApplicationsFlow Cytometry
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DescriptionRat Leukocyte Common Antigen has been shown to exist in different forms on different lymphoid cell types. Rat L-CA on thymocytes shows one main band at 180 kDa, T cells show 4 bands at 180, 190, 200 and 220 kDa. ABIN133316detects a subfraction of the 240 kDa rat L-CA band found only on B lymphocytes. This monoclonal antibody is of particular use in the investigation of the molecular and antigenic heterogeneity of rat L-CA, especially when used in conjunction with other OX antibodies. Four mouse monoclonal antibodies (MRC OX 1, 28, 29 and 30) react with all molecular forms of L-CA and fall into two sets that are non- competitive in binding to L-CA (MRC OX 1, 28, 29 and 30). The antigenic determinants seen by all these antibodies are lost when L-CA is reduced and alkylated. Three antibodies (MRC OX 22, 31, and 32) react selectively with B cells, T cytotoxic cells and about two thirds of T helper cells. OX 22 and OX 31 compete for binding but are non- competitive with OX 32. All of these antibodies bind to a sub-fraction of the 190, 200 and 220 kDa forms of T cell L-CA but not at all to the 180 kDa form of T cells or thymocytes.
ImmunogenRat purified spleen L-CA . Fusion Partner: NSO/U . Donor: BALB/c spleen
Other Namesn/a
Gene, Accession #n/a
Catalog #ABIN133316
Price$286
Order / More InfoCD45RA/B Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

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