CD79a Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | CD79a |
| Clone | IGA-1790R |
| Host Species | Rabbit |
| Reactive Species | cow, human, monkey, mouse, porcine, rat |
| Isotype | IgG |
| Format | unconjugated |
| Size | 100 µg |
| Concentration | 200 µg/mL |
| Applications | Flow Cytometry, Immunofluorescence, Immunohistochemistry, Staining Methods, Western Blotting |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well. Target Information: The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]. |
| Immunogen | A synthetic peptide corresponding to aa 202-216 (GTYQDVGSLNIADVQ) of human CD79a protein. |
| Other Names | IGA|MB-1|B-cell antigen receptor complex-associated protein alpha chain|CD79a antigen (immunoglobulin-associated alpha)|MB-1 membrane glycoprotein|ig-alpha|membrane-bound immunoglobulin-associated protein|surface IgM-associated protein|CD79a molecule|CD79A|B-cell antigen receptor complex-associated protein alpha-chain|Igalpha|Ly-54|Ly54|Ig alpha|immunoglobulin-associated alpha|Cd79a molecule-like|Cd79al|CD79-alpha protein |
| Gene, Accession # | Gene ID: 973, 12518, 281674, 681236, 100190992 |
| Catalog # | ABIN6941270 |
| Price | $575 |
| Order / More Info | CD79a Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
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