APOA1 Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | APOA1 |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 1 mg |
| Concentration | 1.0 mg/mL |
| Applications | ELISA, Immunohistochemistry, Immunoprecipitation, Western Blotting |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background: Anti Apolipoprotein A-I antibody recognizes the gene product of APOA1. Apolipoprotein promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids, an 18-amino acid signal peptide is removed co-translationally and a 6-amino acid propeptide is cleaved post-translationally. Variation in the latter step, in addition to modifications leading to so-called isoforms, is responsible for some of the polymorphism observed. APOA1 is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the C-III gene is transcribed convergently in relation to A-I. Defects in the apolipoprotein A-1 gene are associated with HDL deficiency and Tangier disease. This antibody is suitable for cardiovascular research. Gene Name: APOA1 Target Information: This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. [provided by RefSeq, Jul 2008]. |
| Immunogen | Immunogen: apoLipoprotein Type A-I was isolated from human plasma by density gradient centrifugation followed by HPLC purification. Immunogen Type: Native Protein |
| Other Names | apo-AI|apolipoprotein A1|APOA1|Apolipoprotein A-I|Alp-1|Apoa-1|Brp-14|Ltw-1|Lvtw-1|Sep-1|Sep-2|Sep2|apoA-I|apolipoprotein A-1|preproapolipoprotein A-I|apoa|cb49|wu:fb33f01|zgc:103718|etID309895.5|etID32161.5|apolipoprotein A-Ia|apoa1a|apolipoprotein A-I preproprotein|MGC64335|apolipoprotein A-I S homeolog|apoa1.S|MGC89745|apolipoprotein A-I-like|apolipoprotein A4|apoa4|ApoAI |
| Gene, Accession # | Gene ID: 335 |
| Catalog # | ABIN5596807 |
| Price | $1384 |
| Order / More Info | APOA1 Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
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