Selectin E/CD62e Antibody from ANTIBODIES-ONLINE GmbH

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Antigenic SpecificitySelectin E/CD62e
CloneTEA2-1
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b
Formatphycoerythrin (PE) conjugate
Size100 tests
Concentrationn/a
ApplicationsFlow Cytometry, Immunofluorescence
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DescriptionThe antibody is specific to the human antigen E-selectin (ELAM-1, 115 kDa) that is expressed on activated endothelial cells. The ligand is expressed on neutrophils and may function as an early part in neutrophil binding to the endothelium. This antibody is expressed on cytokine-stimulated endothelium, weakly on unactivated endothelium, and is absent on leukocytes. Target Information: The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008].
Immunogenn/a
Other NamesCD62E|ELAM|ELAM1|ESEL|LECAM2|CD62 antigen-like family member E|E-selectin|ELAM-1|endothelial adhesion molecule 1|endothelial leukocyte adhesion molecule 1|leukocyte endothelial cell adhesion molecule 2|leukocyte-endothelial cell adhesion molecule 2|selectin E|SELE|Selectin E/CD62e|selectin E (endothelial adhesion molecule 1)|selectin|endothelial cell|E-selectin-like|selectin, endothelial cell|si:ch211-260g14.8|uncharacterized protein LOC558139
Gene, Accession #Gene ID: 6401
Catalog #ABIN1112204
Price$704
Order / More InfoSelectin E/CD62e Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

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