NKIRAS2 Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | NKIRAS2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Western Blotting |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | KappaB ras2 Antibody: KappaB ras-1 (κ,B-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with Iκ,B (Iκ,B), an inhibitor of the transcription factor NF-κ,B. Iκ,B exists in two homologous forms, Iκ,B-alpha and Iκ,B-beta, although Iκ,B-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive Iκ,B-alpha-NF-κ,B complexes can shuttle in and out of the nucleus, Iκ,B-beta-NF-κ,B complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the Iκ,B-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of Iκ,B-beta and regulating the rate of degradation of Iκ,B-beta. This antibody is specific for kappaB-ras2 and has no cross-reactivity to kappaB-ras1. Target Information: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation (By similarity). |
| Immunogen | KappaB ras2 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human KappaB ras2. The immunogen is located within the last 50 amino acids of KappaB ras2. |
| Other Names | KBRAS2|kappaB-Ras2|I-kappa-B-interacting Ras-like protein 2|NF-kappa-B inhibitor-interacting Ras-like protein 2|NFKB inhibitor interacting Ras-like protein 2|kappa B-Ras protein 2|NFKB inhibitor interacting Ras like 2|NKIRAS2|NFKB Inhibitor Interacting Ras-Like 2|zgc:92870|2410003M04Rik|4930527H08Rik|D630018G21Rik|NFKB inhibitor interacting Ras like 2 L homeolog|nkiras2.L |
| Gene, Accession # | Gene ID: 28511 |
| Catalog # | ABIN6990382 |
| Price | $519 |
| Order / More Info | NKIRAS2 Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
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