CD44 Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | CD44 |
| Clone | polyclonal |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | phycoerythrin (PE) conjugate |
| Size | 50 µg |
| Concentration | 0.1 mg/ml |
| Applications | Flow Cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | anti-mouse CD44 (Pgp-1, Ly-24) monoclonal antibody recognizes a 95 kDa glycoprotein found on most hematopoietic cells (1). It is thought to be important in the regulation of migratory properties of lymphocytes during development and the regulation of the interaction with bone marrow stromal cells during hematopoiesis (2,3). CD44 functions as a receptor for hyaluronate, although some cells expressing CD44 do not bind hyaluronate (3,4). This antibody has been shown to inhibit the growth of lymphoid and myeloid cells on long term bone marrow cultures (3). It also blocks the adhesive interactions of B cell hybridomas to a cloned stromal line or to hyaluronate coated dishes (4). Target Information: The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]. |
| Immunogen | Bone Marrow Derived Stromal cells (clone BMS2) . Fusion Partner: SP2/0 . Donor: Lou/MN Rat |
| Other Names | CDW44|CSPG8|ECMR-III|HCELL|HUTCH-I|IN|LHR|MC56|MDU2|MDU3|MIC4|Pgp1|CD44 antigen|GP90 lymphocyte homingadhesion receptor|Hermes antigen|cell surface glycoprotein CD44|chondroitin sulfate proteoglycan 8|epican|extracellular matrix receptor III|hematopoietic cell E- and L-selectin ligand|heparan sulfate proteoglycan|homing function and Indian blood group system|hyaluronate receptor|phagocytic glycoprotein 1|CD44 molecule (Indian blood group)|CD44|syndecan 4 (amphiglycan|ryudocan)|syndecan-4|syndecan 4|SDC4|AU023126|AW121933|AW146109|HERMES|Ly-24|Pgp-1|PGP-I|lymphocyte antigen 24|phagocytic glycoprotein I|CD44A|METAA|RHAMM|Cell surface glycoprotein CD44 (hyaluronate binding protein)|CD44-like protein|extracellular matrix receptor-III|lymphocyte surface antigen precursor CD44|XCD44|mutch-i|CD44 molecule (Indian blood group) S homeolog|hyaluronan receptor CD44|cd44.S |
| Gene, Accession # | Gene ID: 12505 |
| Catalog # | ABIN133974 |
| Price | $209 |
| Order / More Info | CD44 Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
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52072 Aachen GERMANY
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