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Antigenic Specificity | Selectin E/CD62e |
Clone | ENA2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 100 µg |
Concentration | n/a |
Applications | Blocking Antibody, Immunoassay, Immunostaining |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ENA2 reacts with E-selectin CD62-E, previous designated the Endothelial Leucocyte Adhesion Molecule-1 (ELAM-1). The antibody reacts with human endothelial cells activated with TNF-alpha, IL-1 or endotoxin. The antibody was found to react also with cells transfected with the E-selectin gene. The antibody inhibits the adhesion of granulocytes both neutrophilic and eosinophilic. Target Information: The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008]. |
Immunogen | n/a |
Other Names | CD62E|ELAM|ELAM1|ESEL|LECAM2|CD62 antigen-like family member E|E-selectin|ELAM-1|endothelial adhesion molecule 1|endothelial leukocyte adhesion molecule 1|leukocyte endothelial cell adhesion molecule 2|leukocyte-endothelial cell adhesion molecule 2|selectin E|SELE|Selectin E/CD62e|selectin E (endothelial adhesion molecule 1)|selectin|endothelial cell|E-selectin-like|selectin, endothelial cell|si:ch211-260g14.8|uncharacterized protein LOC558139 |
Gene, Accession # | Gene ID: 6401 |
Catalog # | ABIN2192128 |
Price | $627 |
Order / More Info | Selectin E/CD62e Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |