Ly6g Antibody from ANTIBODIES-ONLINE GmbH

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Antigenic SpecificityLy6g
CloneRB6-8C5
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2b kappa
Formatphycoerythrin (PE) conjugate
Size25 µg
Concentrationn/a
ApplicationsFlow Cytometry
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DescriptionThe RB6-8C5 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils. In the mouse, the RB6-8C5 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phe- notypic analysis of monocytes, macrophages and granulocytes.Note: The RB6-8C5 antibody has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C. Other reports suggest that this antibody is specific for Ly-6G, without cross-reactivity for Ly-6C (Nagendra S. and Schlueter AJ. 2003. cytometry A, 58(2): 195-200).
Immunogenn/a
Other NamesGr-1|Gr1|Ly-6G|ly-6G.1|lymphocyte antigen 6G|lymphocyte antigen 6 complex, locus G|Ly6g
Gene, Accession #Gene ID: 546644
Catalog #ABIN6961558
Price$70
Order / More InfoLy6g Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

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