CRTC1 Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | CRTC1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 100 µg |
| Concentration | 0.95 mg/mL |
| Applications | ELISA, Western Blotting |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. MECT1 (also known as MucoEpidermoid Carcinoma Translocated 1, Transducer of regulated cAMP response element-binding protein 1, TORC1, and Transducer of CREB protein 1) is a nuclear protein that functions as a transcriptional coactivator for CREB1, which activates transcription through both consensus and variant cAMP response element (CRE) sites. MECT1does not appear to modulate CREB1 DNA-binding activity butTarget Information: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells (By similarity). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons. |
| Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 19-34 of human MECT1 protein. |
| Other Names | MECT1|TORC-1|TORC1|WAMTP1|CREB-regulated transcription coactivator 1|mucoepidermoid carcinoma translocated protein 1|transducer of regulated cAMP response element-binding protein (CREB) 1|CREB regulated transcription coactivator 1|CRTC1|AI413414|R74955|mKIAA0616|mucoepidermoid carcinoma translocated 1|mucoepidermoid carcinoma translocated protein 1 homolog|transducer of CREB protein 1|transducer of regulated cAMP response element-binding protein 1|CREB-regulated transcription coactivator 1-like|fc68c05|pde4cb|si:ch211-255d18.1|si:ch211-255d18.8|wu:fc68c05|CH211-255D18.10|CH211-255D18.9|CREB regulated transcription coactivator 1b|cAMP-specific 3'|5'-cyclic phosphodiesterase 4C|phosphodiesterase 4C|cAMP-specific b|zfTorc1|crtc1b |
| Gene, Accession # | Gene ID: 23373 |
| Catalog # | ABIN129689 |
| Price | $537 |
| Order / More Info | CRTC1 Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
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