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Antigenic Specificity | GAPDH |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | chicken, cow, fish, goat, hamster, human, mouse, porcine, rabbit, rat |
Isotype | n/a |
Format | biotin conjugate |
Size | 40 µg |
Concentration | n/a |
Applications | Western Blotting |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is one of the key enzymes involved in glycolysis. Though expressed differently in different tissues , GAPDH is thought to be a constitutively expressed housekeeping protein. For this reason, GAPDH is often measured as a control in experiments quantifying specific changes in expression of other targets. Recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellular processes such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. GAPDH may also play a role in neurodegenerative pathologies such as Huntingtons and Alzheimer-disease. Some physiological factors, such as hypoxia and diabetes, increase GAPDH expression in certain cell types. Goat Anti-GAPDH [Biotin] Polyclonal Antibody is highly purified from goat antiserum by immunoaffinity chromatography and then conjugated to biotin. The antibody is supplied as a 40 µg aliquot at a concentration of 0.5 mg/ml. Target Information: The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Many pseudogenes similar to this locus are present in the human genome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]. |
Immunogen | n/a |
Other Names | G3PD|GAPD|aging-associated gene 9 protein|peptidyl-cysteine S-nitrosylase GAPDH|glyceraldehyde-3-phosphate dehydrogenase|GAPDH|38 kDa BFA-dependent ADP-ribosylation substrate|BARS-38|BEST:GH12586|CG12055|DmelCG12055|GA3PDH|GADPH|GAP|GAPDH I|GAPDH-1|GAPDH1|GAPDHI|Gapdh43E|gh12586|CG12055-PA|CG12055-PB|G3-P dehydrogenase|Gapdh1-PA|Gapdh1-PB|Glyceraldehyde-3-phosphate dehydrogenase1|glyceraldehyde 3 phosphate dehydrogenase|glyceraldehyde 3 phosphate dehydrogenase 1|glyceraldehyde 3 phosphate dehydrogenase1|glyceraldehyde phosphate dehydrogenase|cb609|mg:bb02e05|wu:fb33a10|wu:ft80f05|bb02e05|KNC-NDS6|G3PDH|glyceraldehyde-3-phosphate dehydrogenase S homeolog|gapdh.S|type I|glyceraldehyde-3-phosphate dehydrogenase, type I|glyceraldehyde-3-phosphate dehydrogenase-like|LOC100404960|olfactory receptor 8K3|LOC614985 |
Gene, Accession # | Gene ID: 2597, 14433, 24383, 374193, 396823, 614985, 100009074, 100860872 |
Catalog # | ABIN1573976 |
Price | $160 |
Order / More Info | GAPDH Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |