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Antigenic Specificity | USP34 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 100 µL |
Concentration | n/a |
Applications | Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | USP34, also named as KIAA0570 and KIAA0729, belongs to the peptidase C19 family. USP34 recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. It is involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. The antibody recognize all these 3 isoforms of USP34. Target Information: Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity). |
Immunogen | Recombinant protein corresponding to Mouse USP34 |
Other Names | deubiquitinating enzyme 34|ubiquitin carboxyl-terminal hydrolase 34|ubiquitin specific protease 34|ubiquitin thioesterase 34|ubiquitin thiolesterase 34|ubiquitin-specific-processing protease 34|ubiquitin specific peptidase 34|USP34|A530081C03Rik|Murr2|U2af1-rs1 region 2|usp36|ubiquitin specific peptidase 34-like |
Gene, Accession # | Gene ID: 17847, 360990 |
Catalog # | ABIN7076115 |
Price | $286 |
Order / More Info | USP34 Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |