Myosin Antibody from ANTIBODIES-ONLINE GmbH
Search, find, compare suppliers for anti-Myosin antibody, protein, ELISA kits.
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| Antigenic Specificity | Myosin |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 100 µL |
| Concentration | 70 mg/mL |
| Applications | ELISA, Immunohistochemistry, Immunoprecipitation, Western Blotting |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background: Myosin is the major component of thick muscle filaments, and is a long asymmetric molecule containing a globular head and a long tail. The molecule consists of two heavy chains each ~200,000 daltons, and four light chains each ~16,000 - 21,000 daltons. Activation of smooth and cardiac muscle primarily involves pathways that increase calcium levels and myosin phosphorylation, resulting in contraction. Myosin light chain phosphatase acts to regulate muscle contraction by dephosphorylating activated myosin light chain. This antibody is specific for the phosphorylated form of myosin light chain. The selected peptide sequence used to generate the polyclonal antibody is located near the amino terminal end of the polypeptide corresponding to the smooth/non-muscle form of myosin regulatory light chain found in cardiac myocytes in addition to smooth and non-muscle cells. This sequence differs from that of the sarcomeric/cardiac form of myosin regulatory light chain that has a different sequence around the phosphorylation site. Human and mouse have almost identical sequences. In human the phosphorylation site is pS19, while in mouse the site maps to pS20. Gene Name: MYL12A Target Information: This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin, it should not be confused with the unconventional myosin-14 (MYO14). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]. |
| Immunogen | Immunogen: Human Myosin Light Chain phospho peptide corresponding to a region near the amino terminus of the human smooth/non-muscle form of myosin regulatory light chain conjugated to Keyhole Limpet Hemocyanin (KLH). Immunogen Type: Peptide |
| Other Names | CG3201|DmMLC_C|DmelCG3201|MyoII|mlc-c|nmELC|CG3201-PA|CG3201-PB|Mlc-c-PA|Mlc-c-PB|Myosin-II|alkali light chain of non-muscle myosin-II|essential light chain-cytoplasmic|essential myosin light chain-cytoplasmic|myosin|myosin II|myosin light chain cytoplasmic|myosin light chain-cytoplasmic|non-muscle myosin II|DFNA4|DFNA4A|MHC16|MYH17|NMHC II-C|NMHC-II-C|PNMHH|MYH14 variant protein|myosin heavy chain|non-muscle IIc|heavy polypeptide 14|myosin-14|non-muscle myosin heavy chain IIc|nonmuscle myosin heavy chain II-C|myosin heavy chain 14|MYH14|hypothetical protein|T22C1.6|MYH1|MYH2|MYH3|MYH4|MYH8|adult|embryonic|MHC (19 AA)|fast skeletal muscle|heavy chain 1|heavy chain 3|heavy polypeptide 1|heavy polypeptide 2|myosin heavy chain 3|skeletal muscle|heavy chain 2|heavy chain 4|heavy polypeptide 4|heavy polypeptide 8|perinatal|myosin-3|myosin, heavy chain 1B, skeletal muscle|MYH1B|myosin 1|ATM1|DROMHC|Dm nmII|DmnmII|Dronm-MII|E(br)|MHC|Mhc-c|Mhc-c1|Myo|Myo II|NMM|Zip|anon-WO0140519.37|l(2)02957|nmMHC|nmy-2|zpr|DmelCG15792|CG15792|zipper|isoform D|CG15792-PD|zip-PD|cytoplasmic myosin-II|enhancer of broad|cytoplasmic myosin|non-muscle myosin|non muscle myosin|myosin heavy chain-cytoplasmic|nonmuscle myosin-II|cytoplasmic myosin II|nonmuscle myosin II|myosin II heavy chain|nonmuscle myosin heavy chain|non-muscle myosin II heavy chain|myosin 2|non-muscle myosin heavy-chain|cytoplasmic myosin heavy chain|nonmuscle myosin-II heavy chain|myosin-heavy-chain-cytoplasmic|isoform A|CG15792-PA|zip-PA|isoform C|CG15792-PC|zip-PC|isoform B|CG15792-PB|zip-PB|2400004E04Rik|II-C|NHMCII|heavy chain 14|myosin, heavy polypeptide 14|myosin heavy chain 9|MYH9 |
| Gene, Accession # | Gene ID: 79784 |
| Catalog # | ABIN5596872 |
| Price | $537 |
| Order / More Info | Myosin Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
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